Sumatriptan 6mg/.5ml 2 x .5ml injections


Sumatriptan is available in multiple forms, including oral tablets, a nasal spray, and subcutaneous injection. The oral tablets come in strengths of 25mg, 50mg, and 100mg, enabling healthcare providers to tailor the treatment to the patient’s specific requirements. By activating serotonin receptors, Sumatriptan causes vascular constriction and reduces inflammation, easing migraine symptoms.



Sumatriptan, commonly sold under the brand name Imitrex, is a prescription medication designed to treat migraine headaches once they start. As a member of the triptan class of drugs, Sumatriptan alleviates the symptoms of migraine by binding to serotonin receptors in the brain, which leads to the constriction of blood vessels in the brain. The medication is effective in relieving the pain, nausea, and light sensitivity that often accompany migraine attacks. It is also used to treat cluster headaches.

Additional information



● The primary use of Sumatriptan is for the acute treatment of migraine attacks with or without aura and the treatment of cluster headaches in adults.

Administration Guidelines


● If taken orally for migraines, the recommended adult dose is a single tablet of 25mg, 50mg, or 100mg taken as soon as symptoms appear. If symptoms persist or return, a second dose may be administered after at least 2 hours, not exceeding 200mg in 24 hours.

Method of Administration

● Oral Tablets: Swallow the tablet whole with water; do not crush or chew.
● Nasal Spray: Administered as a single spray into one nostril.
● Subcutaneous Injection: Injected into the skin, usually at the onset of symptoms.

Dosage Form

● Sumatriptan is available as oral tablets, a nasal spray, and a subcutaneous injection.

Safety Preclusions

Pregnancy and Breastfeeding

● Sumatriptan falls under FDA pregnancy category C and should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Sumatriptan is excreted in human breast milk; hence, caution should be exercised when administered to breastfeeding women.

Long-term Use

● The long-term use of Sumatriptan has not been extensively studied. Its use should be limited to actual migraine or cluster headache episodes.

Drug Interactions

● Combination of Sumatriptan with monoamine oxidase (MAO) inhibitors, other triptans, or selective serotonin reuptake inhibitors (SSRIs) may increase the risk of serotonin syndrome. Patients should report all their current medications to their healthcare provider.

Side Effects

● Typical side effects may include sensations of tingling, heaviness, pressure, flushing, dizziness, fatigue, drowsiness, and weakness.

Serious Side Effects

● Serious side effects can involve changes in heartbeat, blue fingers/toes/nails, cold hands/feet, and unusual changes in mood or behavior. Chest, jaw, or neck tightness, as well as signs of stroke or heart attack, should receive immediate medical attention.


● Store Sumatriptan at room temperature between 15°C and 30°C (59°F and 86°F), protect from light and moisture, and keep it out of the reach of children.

Special Precautions

● Use Sumatriptan with caution in patients with cardiovascular diseases, risk factors for coronary artery disease, or severe hepatic impairment. It should not be used prophylactically or for the treatment of hemiplegic or basilar migraine.


● In the case of an overdose, symptomatic and supportive measures should be employed. Overdose symptoms may include tremors, redness in the arms and legs, loss of coordination, slow breathing, blue-colored skin, and prolonged loss of consciousness. Immediate medical attention is crucial in the event of an overdose.


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