Buy Entresto from Canada

Original price was: $300.00.Current price is: $293.99.

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Description

Entresto (sacubitril/valsartan) is a prescription medication used to treat heart failure with reduced ejection fraction (HFrEF). This innovative drug combines two active ingredients: sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin receptor blocker (ARB). By targeting different pathways involved in heart failure, Entresto helps to improve heart function, reduce symptoms, and decrease the risk of hospitalization related to heart failure.

The dual action of Entresto works by preventing the breakdown of natriuretic peptides, which play a crucial role in regulating blood pressure and fluid balance. At the same time, valsartan blocks the effects of angiotensin II, a hormone that causes blood vessels to constrict, leading to increased blood pressure and strain on the heart. This combination therapy effectively lowers blood pressure, reduces fluid retention, and ultimately improves the heart’s efficiency.

Additional information

Uses of Entresto

Heart Failure: Primarily prescribed for adults with chronic heart failure and reduced ejection fraction, Entresto helps manage symptoms and improve overall cardiac function.
Prevention of Hospitalization: Used to lower the risk of hospitalization due to heart failure and improve survival rates among patients with HFrEF.
Benefits of Entresto

Improved Heart Function
Entresto enhances the heart's ability to pump blood effectively, alleviating symptoms of heart failure, such as shortness of breath and fatigue, leading to a better quality of life.
Reduced Hospitalization Rates
Clinical studies have shown that patients taking Entresto experience fewer hospitalizations due to heart failure, which can significantly impact the overall healthcare burden.
Dual Mechanism of Action
The combination of sacubitril and valsartan provides a comprehensive approach to treating heart failure, targeting multiple pathways to achieve better outcomes than traditional therapies.
How to Use Entresto

Entresto is taken orally, typically twice a day, with or without food. Dosage will depend on individual patient factors, including current medications and health conditions. Follow your healthcare provider’s instructions closely regarding dosing.
Side Effects of Entresto

While many patients tolerate Entresto well, some may experience side effects, including:
Low blood pressure (hypotension)
Elevated potassium levels (hyperkalemia)
Dizziness
Fatigue
Cough
Serious side effects are rare but may include allergic reactions or kidney problems. It is important to report any unusual symptoms to your healthcare provider promptly.
How Entresto Works

Entresto’s unique formulation works by inhibiting neprilysin, which results in increased levels of beneficial natriuretic peptides, promoting vasodilation (widening of blood vessels) and diuresis (increased urine production). At the same time, valsartan blocks the action of angiotensin II, further reducing blood pressure and workload on the heart.
Safety Advice and Precautions

Kidney Function
Entresto can affect kidney function, so regular monitoring of kidney function and electrolytes is recommended, particularly in patients with pre-existing kidney issues.
Pregnancy
Entresto is contraindicated during pregnancy due to potential harm to the fetus. Women of childbearing age should use effective contraception while taking this medication and discuss any pregnancy plans with their healthcare provider.
Blood Pressure Monitoring
Patients should have their blood pressure regularly monitored, as Entresto can lead to hypotension, especially after the initial dose adjustment.
Variants

49 mg/51 mg 60 Tablets, 97 mg/103 mg 60 Tablets
What if You Forget to Take Entresto?

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and resume your regular schedule. Do not take two doses at once.
Overdosing

Overdosing
In case of an overdose, seek immediate medical attention. Symptoms may include severe hypotension or dizziness.
FAQs About Entresto

How long does it take for Entresto to work?
Patients may begin to notice improvements in heart failure symptoms within a few weeks, although optimal benefits may take several months.
Can I take Entresto with other medications?
Entresto may interact with other medications. Always inform your healthcare provider about all the medications you are currently taking to avoid potential interactions.
Are there any dietary restrictions while taking Entresto?
There are no specific dietary restrictions, but it is important to maintain a balanced diet, particularly concerning potassium intake, as Entresto can raise potassium levels.
Is Entresto suitable for all heart failure patients?
Entresto is specifically indicated for patients with HFrEF. Consult your healthcare provider to determine if it is the right medication for your specific condition.

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