Candesartan’s mechanism of action involves blocking the angiotensin II type 1 (AT1) receptors on blood vessels, thus preventing the angiotensin II from triggering a response that leads to vasoconstriction (narrowing of blood vessels). By blocking these receptors, candesartan leads to vasodilation, which reduces blood pressure and eases the workload on the heart, making it beneficial for people with hypertension and heart failure.

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Candesartan is a medication primarily used for the treatment of high blood pressure (hypertension) and heart failure. As a member of the angiotensin receptor blockers (ARBs) class of drugs, it primarily works by blocking the action of a substance in the body called angiotensin II, which causes blood vessels to tighten. By preventing angiotensin II from exerting its effects, candesartan allows blood vessels to relax and widen, which helps to lower blood pressure and improve the efficiency of the heart. This medication is available in tablet form and should be taken under the guidance of a healthcare professional to ensure its safe and effective use.

Additional information


Hypertension: Candesartan is used to manage high blood pressure and may be prescribed as part of a combination therapy with other blood pressure-lowering medications. Heart Failure: It can also treat heart failure in patients who cannot tolerate angiotensin-converting enzyme (ACE) inhibitors. To achieve the best results, patients should: 1. Take the medication as prescribed, with or without food. 2. Be consistent with the time of day they take the medication to maintain stable drug levels in the blood. 3. Continue taking the medication even if they feel well, as hypertension often has no symptoms.

Side Effects

● Dizziness or lightheadedness, especially after the first dose or when the dose is increased ● Back pain ● Cold or flu-like symptoms Serious side effects requiring immediate medical attention consist of: ● Swelling of the face, eyes, lips, or tongue ● Difficulty breathing or swallowing ● Significant drop in blood pressure (hypotension)


Candesartan should be stored in its original container, tightly closed, and at room temperature. It should be avoided from excess heat, moisture (not in the bathroom), and direct light. Ensure the medication is out of reach of children and pets.

Special Precautions

Before starting treatment with candesartan, patients should discuss with their healthcare provider: ● Any history of allergies to ARBs or any other medications. ● Their complete medical history, especially concerning kidney problems, liver disease, dehydration, electrolyte imbalances, or if they are on a salt-restricted diet. ● All current medications, prescription or over-the-counter, vitamins, and herbal supplements to avoid potential interactions. Patients with kidney disease, pregnant women, or those planning to become pregnant or breastfeeding should use candesartan with caution and under strict medical supervision.


An overdose of candesartan could lead to symptoms such as extremely low blood pressure (hypotension), dizziness, increased heart rate, or kidney failure. In case of suspected overdose, immediate medical attention is required. Treatment may involve supportive care, such as intravenous fluids or medications to increase blood pressure and monitoring of heart and kidney functions.


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