Captopril works by inhibiting the angiotensin-converting enzyme, which is responsible for the production of angiotensin II — a substance that narrows blood vessels and raises blood pressure. By decreasing the levels of angiotensin II, captopril reduces blood vessel constriction, leading to lower blood pressure and reduced strain on the heart.

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Captopril is a medication commonly used to treat high blood pressure (hypertension), heart failure, and kidney problems caused by diabetes. It belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors, which help to relax blood vessels and improve blood flow, thereby lowering blood pressure and making it easier for the heart to pump blood. This medication is available in tablet form and should be taken under the supervision of a healthcare provider for safe and effective treatment.

Additional information


Hypertension: Captopril is prescribed to manage high blood pressure. It can be used alone or in combination therapy with other antihypertensive agents. Heart Failure: It is used to treat heart failure to improve symptoms and increase survival after a heart attack. Diabetic Kidney Disease: Captopril can be used to treat kidney problems caused by Type 1 and Type 2 diabetes. Patients should: ● Take the medication exactly as prescribed, on an empty stomach, one hour before, or two hours after meals. ● Be consistent in taking the medication to maintain effective control of blood pressure. ● Not stop taking the medication even if they feel well, as hypertension is often asymptomatic.

Side Effects

● Cough ● Taste disturbances ● Rash Serious side effects that require immediate attention can include: ● Swelling of the mouth, tongue, face, or limbs (angioedema) ● Difficulty breathing ● Signs of infection (fever, sore throat) ● Hyperkalemia (high levels of potassium in the blood)


Captopril should be stored in its original packaging, at room temperature, away from moisture and direct sunlight, and out of reach of children and pets.

Special Precautions

Before beginning treatment with captopril, patients should inform their healthcare provider about: ● Any allergies, particularly to ACE inhibitors or other medications. ● A complete medical history, including liver or kidney disease, blood filtering procedures (dialysis), blood or bone marrow disorders, immune system diseases, collagen vascular disease, or a high potassium blood level. ● All medications they are currently using, including prescription drugs, over-the-counter products, vitamins, and herbal supplements to avoid interactions. Captopril should be used with caution in patients with kidney impairment, and it is generally advised against in pregnant or breastfeeding women due to possible harm to the fetus or baby.


Symptoms of an overdose of captopril may include severe dizziness, fainting, and shock due to a severe drop in blood pressure. If an overdose is suspected, prompt medical intervention is necessary. Overdose treatment typically includes supportive measures such as intravenous fluids and medications to stabilize blood pressure, and close monitoring of vital signs and electrolytes.


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