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Imbruvica (Ibrutinib)

$484.00

Ibrutinib is a medication employed in the treatment of several types of cancers, including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and Waldenstrom’s macroglobulinemia (WM).

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Description

Ibrutinib is a medication employed in the treatment of several types of cancers, including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and Waldenstrom’s macroglobulinemia (WM). Classified as a kinase inhibitor, it operates by inhibiting the activity of an aberrant protein that triggers the proliferation of cancer cells, thus impeding their spread.

Additional information

Usage

Usage
-Ibrutinib is administered orally in capsule form, typically once daily at the same time each day. Adhere closely to the instructions on your prescription label; consult your doctor or pharmacist for clarification if needed. Take Ibrutinib precisely as prescribed; do not alter the dosage or frequency without your doctor's approval. Swallow the capsules whole with a full glass of water; do not open, break, or chew them.
Your doctor may adjust your Ibrutinib dosage during your treatment based on its effectiveness and any side effects. Maintain open communication with your doctor regarding your treatment experience. It's important to continue taking Ibrutinib even if you feel well and not discontinue it without consulting your doctor. You can also request a copy of the manufacturer's patient information from your pharmacist or doctor.

Side Effects

Side Effects
Ibrutinib may lead to side effects. Should any of these symptoms endure or worsen, please notify your doctor:
• Diarrhea
• Nausea
• Constipation
• Vomiting
• Stomach pain
• Heartburn or indigestion
• Decreased appetite
• Excessive tiredness or weakness
• Muscle, bone, and joint pain
• Muscle spasms
• Edema in the hands, feet, ankles, or lower legs.
• Rash
• Itching
• Mouth and throat sores
• Anxiety
• Difficulty sleeping
Specific side effects are more serious. If you experience any of the following symptoms, contact your doctor immediately or seek emergency medical attention:
• Unusual bruising or bleeding
• Pink, red, or dark brown urine
• Bloody or black, tarry stools
• Nosebleeds
• Bloody vomit or vomiting blood or coffee ground-like material
• Seizures
• Rapid or irregular heartbeat
• Shortness of breath
• Chest discomfort
• Dizziness, lightheadedness, or fainting
• Changes in vision
• Persistent headache
• Fever, chills, cough, or signs of infection
• Confusion
• Altered speech
• Reduced urination
Ibrutinib may increase the risk of certain skin or organ cancers. Discuss the potential risks of taking Ibrutinib with your doctor.

Storage

Storage
-Store this medication in its original container, securely closed, and out of children's reach. Keep it at room temperature, away from light, excessive heat, and moisture, but not in the bathroom. Dispose of unnecessary medication using safe methods to prevent accidental consumption by pets or others. Do not flush it down the toilet; instead, utilize a medicine take-back program. Consult your pharmacist or contact your local waste disposal authorities for information on available take-back programs in your area. Always safeguard medication from children by using child-resistant containers and promptly storing them in a secure, elevated location out of children's view and reach.

Special Precautions

Special Precautions:
Before starting Ibrutinib, please inform your doctor and pharmacist of the following:
• Any allergies to Ibrutinib, other medications, or ingredients in Ibrutinib capsules. You can ask your pharmacist for a list of ingredients.
• All prescription and non-prescription medications, vitamins, supplements, and herbal products you are currently using or plan to use. Specifically, mention:
• Blood thinners like warfarin (Coumadin, Jantoven).
• Antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), and voriconazole (Vfend).
• Antiplatelet drugs like clopidogrel (Plavix), prasugrel (Effient), ticagrelor (Brilinta), and ticlopidine.
• Other medications like aprepitant (Emend), boceprevir (Victrelis), carbamazepine (Carbatrol, Epitol, Tegretol, Teril), ciprofloxacin (Cipro), clarithromycin (Biaxin, Prevpac), crizotinib (Xalkori), digoxin (Lanoxin), diltiazem (Cardizem, Cartia, Tiazac, others), erythromycin (E.E.S., Erythrocin, others), imatinib (Gleevec), hypertension medications, certain HIV/AIDS drugs, nefazodone, phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rifamate, Rimactane, others), telaprevir (no longer available in the U.S.; Incivek), verapamil (Calan, Covera, in Tarka, others), and telithromycin (no longer available in the U.S.; Ketek).
• Herbal products, especially St. John's Wort.
• Any infections or recent surgeries.
• Smoking habits.
• Medical history, including diabetes, irregular heartbeat, high blood pressure, high cholesterol, bleeding disorders, and heart, kidney, or liver conditions.
Additionally:
• If you are pregnant, planning to become pregnant, breastfeeding, or planning to father a child. Pregnancy should be avoided while taking Ibrutinib. Pregnancy tests for females and birth control measures are necessary during treatment and for one month after discontinuing the medication. Males and their female partners should also use birth control during treatment and for one month after the last dose.
• If you require surgery, including dental procedures, inform your healthcare provider or dentist that you are taking Ibrutinib. Your doctor may advise discontinuing Ibrutinib 3 to 7 days before the surgery or procedure.

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