Actoplus Met: Empowering Healthier Lives with Diabetes | Better You Rx

Actoplus Met and Your Health: The Powerful Team for Diabetes Management

In addition to a healthy diet and regular exercise, pioglitazone and metformin are combined to treat high blood sugar levels brought on by type 2 diabetes. Pioglitazone functions by improving the way your body uses insulin. Metformin decreases the release of stored sugar from the liver, decreases the absorption of sugar from the stomach, and improves how well your body uses sugar. This medication does not help patients with type 1 diabetes or diabetes that is insulin-dependent.

Functions of Actoplus Met

Two antidiabetic drugs that help decrease blood sugar make up Actoplus Met:

  • A biguanide called metformin helps you utilize your body’s natural insulin more effectively by reducing the amount of sugar your body produces or absorbs.
  • A thiazolidinedione called pioglitazone improves how effectively your body uses insulin to decrease blood sugar.

What adverse effects does Actoplus Met have?

Significant Side Effects

If you encounter any of the following, get in touch with your doctor right away:

Shortness of breath, unexpected swelling, fatigue, and abrupt weight gain are symptoms of heart failure.

  • Lactic acidosis symptoms include rapid breathing, a fast or slow heartbeat, abnormal heartbeat, an agitated stomach or vomiting, extreme sleepiness, shortness of breath, extreme fatigue or weakness, dizziness, chilly, and muscle pain.
  • Bladder cancer symptoms include pain when urinating, the need to urinate frequently, and blood in the urine.
  • Liver issues include nausea or vomiting, stomach pain, unusual fatigue, appetite loss, dark urine, and yellowing of the skin or whites of the eyes.
  • Macular edema is a diabetic eye disorder that causes swelling, causes vision abnormalities, and blurriness.

As your body becomes accustomed to the drug, the following adverse effects could improve. If you continue to experience these symptoms or worsen over time, call your doctor immediately.

Typical Adverse Effects

  • A cold-like illness
  • Inflation
  • Vomiting
  • Migraine
  • Adding pounds

Additional Effects

  • A sinus condition
  • A throatache
  • Muscle ache
  • Back ache
  • Chest ache

Actoplus Met’s benefits and drawbacks


  • Lowers A1C levels (average blood sugar level over three months) more than metformin (Glucophage) or pioglitazone (Actos) alone.
  • For convenience, combines two drugs into a single pill.
  • Obtainable as a less expensive generic


  • May result in bloating, edema, or weight gain
  • If you have a history of heart failure or bladder cancer, this is not a good option.
  • Not utilized in the management of type 1 diabetes

Tips for Actoplus Met from pharmacists

  • Actoplus Met frequently causes stomach upset. To reduce the likelihood of experiencing stomach distress, take the tablets with meals.
  • Continue your healthy eating and exercise routine while taking Actoplus Met for the greatest outcomes.
  • It may take a few months before you notice all of the medication’s effects on your blood sugar levels.
  • When using this drug, limit your alcohol consumption. You run the danger of developing lactic acidosis, a potentially fatal side effect, if you drink too much or over an extended period of time.
  • If your body is under stress, such as a fever, injury, infection, or surgery, notify your doctor straight away. Your dose may need to be modified.
  • Be sure to go to your scheduled checkups and get any bloodwork completed. This will demonstrate to your doctor how effectively Actoplus Met is helping you.
  • Regularly check your blood sugar. Both you and your provider will benefit from keeping a record of your blood sugar readings.

Dosing formulations for Actoplus Met


  • 15mg/500mg
  • 15mg/850mg

Ordinary Actoplus Met dosage

The dosage of Actoplus Met may change based on your prior diabetes treatment regimen and any additional medical conditions you may have. 15 mg/500 mg (pioglitazone/metformin) by mouth twice daily or 15 mg/850 mg (pioglitazone/metformin) by mouth once daily is the usual starting dose. If necessary, your doctor will gradually increase your dosage based on how you react to the drug. The maximum daily dose of pioglitazone/metformin is 45 mg/2,550 mg.

Actoplus Met frequently asked questions

Actoplus Met may be taken without food.

In order to avoid stomach distress, it is advisable to take Actoplus Met with food. When taking it without meals, you run the risk of developing nausea and diarrhea.

Am I allowed to discontinue taking Actoplus Met on my own?

Stopping Actoplus Met can cause your blood sugar to spike once more because it lowers blood sugar. Before quitting it on your own, discuss any worries or troublesome side effects with your doctor. The negative effects of this medicine are typically transient or can be mitigated by switching to a different prescription.

When taking Actoplus Met, is alcohol permitted?

Alcohol can increase the risk of lactic acidosis, a condition when the body produces an excessive quantity of lactic acid. Avoid consuming high amounts of alcohol (either very frequently or a lot in a short period of time) when using Actoplus Met as this condition can sometimes have dangerous adverse effects.

Actoplus Met: Does it harm the kidneys?

Actoplus Met is eliminated from your body through the kidneys, so let your doctor know if you have ever had kidney issues prior to taking this medicine. Healthy kidneys are not known to be impacted by Actoplus Met. While taking it, you must have routine blood tests to ensure the condition of your kidneys.

Choose Better You Rx Pharmacy as your healthcare partner to embark on a path of effective diabetes management. We are dedicated to your well-being and equipped with the expertise to provide personalized guidance tailored to your unique needs. Your health is your greatest wealth, and we’re here to help you achieve the best version of yourself.

Don’t miss out on the chance to take control of your diabetes with Actoplus Met. Trust Better You Rx Pharmacy for top-notch care and unwavering support on your journey to a healthier, happier life. Your well-being is our priority, and we’re here to empower you every step of the way.

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