A diabetes drug called rosiglitazone may make congestive heart failure worse. Before beginning rosiglitazone therapy, patients should inform their doctor if they have congestive heart failure, heart defects, high blood pressure, coronary artery disease, heart attacks, irregular heartbeats, or sleep apnea. Congestive heart failure symptoms include weight gain, shortness of breath, swelling, stomach ache, needing additional pillows, frequent dry coughs, trouble thinking, frenzied heartbeat, difficulty moving or exercising, and increasing exhaustion. It’s crucial to review the dangers of rosiglitazone use with your doctor.
Why Prescribed
To treat type 2 diabetes (a condition in which the body does not use insulin usually and cannot control the quantity of sugar in the blood), rosiglitazone is sometimes used with a diet and exercise program as well as one or more other drugs. The drug rosiglitazone belongs to the thiazolidinediones class of drugs. It functions by enhancing the body’s sensitivity to insulin, a naturally occurring chemical that aids with blood sugar regulation. Both diabetic ketoacidosis, a hazardous illness that may develop if high blood sugar is not treated, and type 1 diabetes, a condition in which the body does not generate insulin and can therefore not control the quantity of sugar in the blood, are not treated with rosiglitazone.
People with diabetes and high blood sugar over time may experience serious or fatal complications, such as heart disease, stroke, kidney issues, nerve damage, and vision issues. It may be possible to control your diabetes and enhance your health by taking medication(s), making lifestyle changes (such as diet, exercise, and quitting smoking), and monitoring your blood sugar frequently. This treatment may also lower your risk of heart attack, stroke, kidney failure, nerve damage (resulting in numb, cold legs or feet and diminished sex capacity in both men and women), eye issues, such as changes in eyesight or blindness, or gum disease, which are all symptoms of diabetes. The optimal strategy to manage your diabetes will be discussed with you by your doctor and other healthcare professionals.
How to Use it
An oral tablet is available for rosiglitazone. Typically, it is taken once or twice a day, with or without food. Every day, take rosiglitazone around the same time(s). Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Rosiglitazone should only be used as prescribed. Never take it in larger or fewer amounts or more frequently than directed by your doctor. Depending on how your body reacts to the drug after 8 to 12 weeks, your doctor may raise your rosiglitazone dosage.
Although it does not treat type 2 diabetes, rosiglitazone aids in its management. Your blood sugar may need to drop for two weeks before you start feeling the full effects of rosiglitazone, which might take three to six months or longer. Rosiglitazone should still be taken even if you are feeling OK. Without consulting your doctor, do not discontinue taking rosiglitazone.
Unique Precautions
Prior to consuming rosiglitazone,
- If you have an allergy to rosiglitazone, any other medications, or any of the ingredients in rosiglitazone tablets, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
- Be sure to let your doctor and pharmacist know what prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you currently use or intend to use. Mention any of the following: rifampin (Rifadin, Rimactane, in Rifamate); gemfibrozil (Lopid); insulin or other diabetes medications; medications for high blood pressure, high cholesterol, heart failure, or prevention of heart attack or stroke. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
- If you have or have ever had any of the conditions listed in the IMPORTANT WARNING section, diabetic eye diseases such as macular edema (swelling of the back of the eye), liver illness, or any other medical condition, please let your doctor know. If you have ever taken troglitazone (Rezulin, no longer available in the United States), be sure to let your doctor know, especially if you discontinued due to negative effects.
- Be sure to let your doctor know if you’re nursing a baby or expecting a baby. Call your doctor if you get pregnant while taking rosiglitazone.
- You should be aware that rosiglitazone may increase your chance of getting pregnant even if you don’t have regular monthly periods or have a medical condition that prevents you from ovulating (releasing an egg from the ovaries) if you haven’t yet gone through menopause (change of life; end of monthly menstrual periods). Consult your doctor about birth control options that are right for you.
Particular Diet
Make sure to abide by all dietary and exercise advice given to you by your physician or nutritionist. It’s crucial to maintain a nutritious diet, exercise frequently, and, if required, reduce weight. This will aid in managing your diabetes and enhance Rosiglitazone’s efficacy.
Untaken Dose
If you miss a dosage, take it as soon as you recall. If the next dose is due, skip the missing one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.
Adverse effects
Your blood sugar levels may alter as a result of this drug. You should be aware of the signs of low and high blood sugar as well as what to do if you experience these signs. Rosiglitazone could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:
- Migraine
- a runny nose and more cold signs
- A throat ache
- Backache
Some adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms or any of those detailed in the IMPORTANT WARNING section:
- discomfort in the stomach, back, neck, arm, or jaw
- Chest ache
- shivering uncontrollably
- Insomnia; dizziness
- Appetite loss
- vomiting
- gagging
- Stomach ache
- Bloody urine
- a yellowing of the eyes or skin
- alterations in vision
- Loss of vision
- Fair skin
- wooziness
- Swelling of the neck, lips, tongue, eyes, or face
- A hoarse voice
- breathing or swallowing issues
- hives
- tingling
- fever
- Blistering
Other negative effects of rosiglitazone are possible. If you encounter any odd issues while taking this medicine, contact your doctor right away. If you use rosiglitazone, your risk of fracture may rise; these fractures typically occur in the upper arms, hands, or feet. Consult your doctor about the potential side effects of this medicine as well as measures to maintain bone health while you’re receiving treatment.
Overdose
Call the poison control hotline if you overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.
Additional Details
Keep all of your appointments with the lab, your physician, and your eye physician. To monitor your body’s reaction to rosiglitazone, your doctor may likely request routine eye exams and specific laboratory testing. You should routinely monitor your blood sugar and glycosylated hemoglobin to see how rosiglitazone is working for you. Your physician might also advise you on how to measure your blood sugar levels at home in order to monitor your reaction to rosiglitazone. Pay close attention to these guidelines.
Wearing a diabetes identity bracelet will ensure that you receive the right care in an emergency. No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist. You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.
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