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Description

Linaclotide is prescribed to adults for the management of irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). IBS-C is characterized by abdominal discomfort, bloating, and infrequent or challenging bowel movements, while CIC involves infrequent or difficult bowel movements lasting for three months or more, unrelated to an underlying condition or medication. Linaclotide is classified as a guanylate cyclase-C agonist medication. Its mechanism of action involves enhancing the movement of food and waste through the stomach and intestines.

Additional information

Usage	Usage Linaclotide is available in capsule form for oral administration. Typically, it is taken once daily on an empty stomach, at least thirty minutes prior to the first meal of the day. To maintain consistency, take linaclotide at approximately the same time each day. Comply with the instructions on your prescription label diligently, and if there's any part you don't understand, consult your doctor or pharmacist for clarification. Adhere to the prescribed dosage precisely; do not exceed or reduce it, and do not take it more frequently than directed by your doctor. Ingest the capsules whole, and refrain from breaking, chewing, or crushing them. Linaclotide effectively manages the symptoms of IBS-C and CIC, but it does not provide a cure for these conditions. You may notice improvements in your constipation symptoms within one week, although it may take a bit longer for your abdominal discomfort to subside. It's important to continue taking linaclotide even if you start feeling better. Do not discontinue linaclotide without consulting your doctor, as your symptoms could return within about one week if you stop taking it.
Side Effects	Side Effects Linaclotide may lead to side effects. If you encounter any of the following symptoms and they are either severe or persistent, inform your doctor: • Diarrhea • Abdominal pain • Sensation of fullness or pressure, accompanied by swelling, in the stomach region • Gas • Headache Certain side effects can be grave. In the event that you experience any of the following symptoms, discontinue linaclotide use immediately and contact your doctor or seek urgent medical attention: • Unusual or severe abdominal pain • Bright red or black, tarry stools • Hives Linaclotide could potentially induce other side effects. Should you encounter any unusual issues while taking this medication, consult your doctor.
Storage	Storage Ensure you store this medication as follows: • Keep it in the original container, tightly sealed, and beyond the reach of children. • Store it at room temperature, away from excessive heat and moisture (avoid the bathroom). • Do not remove the desiccant (drying agent) from the bottle, if provided. To dispose of any unneeded medications safely and prevent accidental ingestion by pets, children, or others, follow these guidelines: • Avoid disposing of the medication by flushing it down the toilet, please. • Consider participating in a medicine take-back program, which can be discussed with your pharmacist or local garbage/recycling department. Given that certain medication containers, like weekly pill organizers and those for eye drops, creams, patches, and inhalers, may not be child-resistant and can be easily opened by young children, it's crucial to: • Always secure safety caps. • Store the medication in a secure location that is both elevated and out of sight, away from children's reach.
Special Precautions	Special Precautions Before using linaclotide, it is important to: • Inform your doctor and pharmacist about any allergies you have, including allergies to linaclotide, other medications, or any of the ingredients in linaclotide capsules. You can check the Medication Guide for a list of ingredients. • Share a comprehensive list of all prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are currently taking or planning to take with your doctor. Your doctor may need to adjust your medication doses or closely monitor you for potential side effects. • Discuss any history of stomach or intestinal blockages with your doctor, as taking linaclotide may not be advisable in such cases. • Inform your doctor about any other medical conditions you have or have had in the past. • Let your doctor know if you are pregnant, planning to become pregnant, or currently breastfeeding. If you become pregnant while using linaclotide, contact your doctor promptly.