Hydralazine directly relaxes the blood vessels, allowing them to widen or dilate. This vasodilatory action reduces the pressure within the arterial walls, lowering overall blood pressure. Unlike many other antihypertensives, it does not reduce heart rate. Still, it focuses on easing the workload on the heart and improving blood flow, making it a beneficial option for certain heart conditions.

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Hydralazine, commonly recognized under various brand names such as Apresoline, is a medication primarily used to treat high blood pressure and heart failure. As an antihypertensive, it plays a crucial role in managing conditions that could lead to heart disease, stroke, and other serious health problems. Available by prescription, hydralazine is offered in several forms, including oral tablets and injectables, catering to different medical needs and scenarios.

Additional information


Hydralazine is prescribed for:

● The management of essential hypertension (high blood pressure without a known cause)
● The treatment of hypertensive crisis (a severe increase in blood pressure that can lead to stroke or heart damage)
● As a part of therapy for heart failure, especially in cases where other treatments may not be suitable

Patients are generally advised to:

● Follow the dosage and administration instructions as given by their healthcare provider
● Monitor their blood pressure regularly to ensure the medication's effectiveness


● Hydralazine may cause a rapid heart rate (tachycardia) or palpitations, particularly at higher doses
● It can lead to a phenomenon called sodium and water retention, which could potentially diminish its effectiveness in lowering blood pressure unless properly managed, often with the use of diuretics
● Patients with a history of coronary artery disease should exercise caution, as the medication might provoke angina or myocardial infarction

Side Effects

● Headache
● Dizziness or lightheadedness
● Nausea
● Flushing or feeling of warmth

Serious side effects that require medical attention can encompass:

● Lupus-like syndrome (a condition resembling lupus, an autoimmune disease)
● Swelling (edema)
● Heart complications like angina or myocardial infarction
● Hematological issues, such as a decrease in white blood cells


● Store hydralazine at room temperature, ideally between 20°C to 25°C (68°F to 77°F), while keeping it away from excessive heat, light, and moisture
● Ensure the medication is securely out of reach of children and pets and stored in a locked cabinet or area for safety

Special Precautions

Before initiating treatment with hydralazine, it's important to discuss with your healthcare provider if:

● You have any pre-existing conditions such as heart disease, kidney disease, or lupus
● You are taking other medications or supplements to prevent potential interactions
● You are pregnant, planning to become pregnant, or breastfeeding, as it's crucial to weigh the benefits against the potential risks to the baby


Symptoms of a hydralazine overdose might include severe hypotension (very low blood pressure), tachycardia (rapid heart rate), headache, and dizziness. In the event of a suspected overdose, it is vital to seek immediate medical intervention. Contact emergency services or head to the nearest emergency room, providing them with all necessary details, including the amount of hydralazine consumed and the time of ingestion.


100 Tablets


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