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Sitagliptin is prescribed in conjunction with dietary adjustments and physical activity, and at times in combination with other drugs, to reduce elevated blood sugar levels in individuals diagnosed with type 2 diabetes. This condition occurs when blood sugar remains excessively high due to the body’s inadequate production or utilization of insulin. Sitagliptin is categorized under the class of drugs referred to as dipeptidyl peptidase-4 (DPP-4) inhibitors. Its mode of action involves augmenting the levels of specific natural substances responsible for lowering elevated blood sugar.

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Description

Sitagliptin is prescribed in conjunction with dietary adjustments and physical activity, and at times in combination with other drugs, to reduce elevated blood sugar levels in individuals diagnosed with type 2 diabetes. This condition occurs when blood sugar remains excessively high due to the body’s inadequate production or utilization of insulin. Sitagliptin is categorized under the class of drugs referred to as dipeptidyl peptidase-4 (DPP-4) inhibitors. Its mode of action involves augmenting the levels of specific natural substances responsible for lowering elevated blood sugar.

In the long term, individuals with diabetes and persistently high blood sugar are susceptible to severe or life-threatening complications, including heart disease, strokes, kidney impairments, nerve damage, and eye-related issues. To effectively manage diabetes and enhance overall health, a combination of medication(s), lifestyle modifications (such as dietary adjustments, regular exercise, and smoking cessation), and routine blood sugar monitoring is recommended. This comprehensive approach can also diminish the risk of experiencing diabetes-related complications, such as kidney dysfunction, nerve damage (manifesting as numbness or cold extremities and reduced sexual function in both men and women), eye complications that may include vision alterations or loss, and gum diseases. Your doctor and healthcare team will collaborate with you to determine the optimal strategy for managing your diabetes.

Additional information

Usage

Sitagliptin is presented in tablet form for oral consumption, and it is typically prescribed for once-daily use, with or without food. It is advisable to take Sitagliptin at approximately the same time each day. To ensure the appropriate usage of this medication, carefully adhere to the instructions provided on your prescription label, and don't hesitate to seek clarification from your doctor or pharmacist regarding any unclear aspects.
Please adhere to the prescribed Sitagliptin dosage precisely as directed by your healthcare provider. It's essential to note that while Sitagliptin aids in regulating elevated blood sugar levels, it does not provide a cure for diabetes. Thus, it is vital to continue taking Sitagliptin even if you are feeling well. Never discontinue Sitagliptin without consulting your doctor. For additional information, you can request a copy of the manufacturer's patient information from your pharmacist or doctor.
Side Effects

Sitagliptin usage may lead to potential side effects. If any of these symptoms persist or become bothersome, it is advisable to inform your doctor promptly:
• Nasal congestion or a runny nose
• Sore throat
• Headache
• Diarrhea
• Nausea
• Joint pain
It's essential to be aware that certain side effects may be more severe. If you encounter any of the following symptoms, discontinue Sitagliptin and promptly contact your healthcare provider:
• Persistent pain that initiates in the upper left or middle section of the abdomen but may radiate to the back
• Vomiting
• Loss of appetite
• Rash
• Hives
• Facial, lip, tongue, or throat swelling
• Breathing difficulties or trouble swallowing
Furthermore, Sitagliptin may potentially induce other side effects. If you experience any unusual or unanticipated issues while taking this medication, do not hesitate to reach out to your doctor for guidance and assessment.
Storage

Ensure this medication remains stored in its original container, securely sealed, and placed out of the grasp of children. Keep it at room temperature, away from excessive heat and moisture, avoiding storage in the bathroom.
Proper disposal of unused medications is essential to prevent accidental ingestion by pets, children, or others. Do not flush this medication down the toilet, as it can harm the environment. Instead, the recommended method for medication disposal is through a medicine take-back program. Consult your pharmacist or get in touch with your local garbage/recycling department to inquire about available take-back programs in your community.
Remember to keep all medications hidden and out of the reach of children, as many containers (including those for eye drops, creams, patches, and inhalers) may not be child-resistant and can be easily opened by young children. To safeguard young children from accidental poisoning, always secure safety caps and promptly place the medication in a secure location, ideally in an elevated and out-of-sight area.
Special Precaution

Prior to initiating sitagliptin, it is essential to:
• Inform both your healthcare provider and pharmacist if you have any known allergies to sitagliptin or other medications.
• Provide your healthcare provider and pharmacist with a comprehensive list of all prescription and nonprescription medications, vitamins, dietary supplements, and herbal products you are currently taking or plan to use. Particular attention should be given to medications like digoxin (Lanoxicaps, Lanoxin), insulin, and specific oral diabetes medications, including acetohexamide, chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol, in Metaglip), glyburide (Diabeta, Glycron, Micronase), tolazamide (Tolinase), and tolbutamide. Adjustments to your medication dosages may be necessary, or your healthcare provider may closely monitor you for potential side effects.
• Inform your healthcare provider if you consume or have ever consumed excessive amounts of alcohol, as well as any history of diabetes, diabetic ketoacidosis (a severe condition that can occur when blood sugar levels are excessively high), pancreatitis (inflammation of the pancreas), gallstones, elevated triglyceride levels (fatty substances) in your blood, or kidney disease.
• Notify your healthcare provider if you are currently pregnant, planning to become pregnant, or breastfeeding. If you become pregnant while taking sitagliptin, it is crucial to promptly contact your doctor.
• If you are scheduled for any form of surgery, including dental procedures, it is imperative to inform the performing healthcare professional that you are using sitagliptin.
• Discuss with your healthcare provider the appropriate steps to take in case of injury or the development of a fever or infection, as these circumstances can impact your blood sugar levels.
• Seek guidance from your healthcare provider regarding the symptoms of both high and low blood sugar, as well as other potential complications related to diabetes. Ensure you are knowledgeable about the actions to take if you experience these symptoms and the preventive measures to avoid these conditions.

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