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Lumakras (Sotorasib)

$21,186.00

Sotorasib is prescribed to adults with non-small cell lung cancer (NSCLC) that has metastasized or is inoperable after prior treatments. It belongs to the class of drugs known as KRAS inhibitors, working to disrupt the abnormal protein driving cancer cell multiplication, ultimately slowing or halting cancer spread.

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Description

Sotorasib is prescribed to adults with non-small cell lung cancer (NSCLC) that has metastasized or is inoperable after prior treatments. It belongs to the class of drugs known as KRAS inhibitors, working to disrupt the abnormal protein driving cancer cell multiplication, ultimately slowing or halting cancer spread.

Additional information

Usage

Usage
Sotorasib is provided in tablet form for oral administration, typically taken once daily, with or without food. Maintain a consistent daily schedule. Adhere to the instructions on your prescription label, seeking clarification from your doctor or pharmacist as needed. Do not alter the tablets; swallow them whole. If swallowing is difficult, place the tablets in a glass of 4 ounces (120 mL) of non-carbonated, room-temperature water (no other liquids). Stir until the tablets break into small pieces, then drink the mixture immediately or within 2 hours of preparation. Rinse the glass with an additional 4 ounces (120 mL) of water to ensure you consume the entire dose. If vomiting occurs after taking sotorasib, do not take another dose; resume your regular schedule the next day. Your doctor may adjust your sotorasib treatment based on your response and side effects. Continue taking sotorasib as directed, even if you feel well. Always consult your doctor before discontinuing treatment. Request the manufacturer's patient information from your pharmacist or doctor.

Side Effects

Side Effects
Sotorasib may result in side effects. If any of these symptoms continue or get worse, notify your doctor:
• Diarrhea
• Vomiting
• Nausea
• Constipation
• Loss of appetite
• Stomach pain
• Fatigue
• Muscle or bone pain
• Joint pain
• Rash Some side effects require immediate medical attention.

Reach out to your doctor or seek immediate medical attention if you encounter:
• Yellowing of the skin or eyes, dark-colored urine, easier bruising or bleeding, reduced appetite, or pain on the right side of the abdomen
• Shortness of breath, cough, or fever Sotorasib may have other side effects. Discuss any unusual concerns with your doctor during treatment.

Storage

Storage
Store this medication in its original container, tightly sealed, and out of children's reach. Keep it at room temperature, away from light, excessive heat, and moisture (avoid storing it in the bathroom).
To protect children from accidental ingestion, use child-resistant caps and store the medication out of their sight and reach. For safe disposal of unused medication, do not flush it down the toilet. Instead, consult your pharmacist or local waste disposal services for proper disposal methods.

Special Precautions

Special Precautions
Before starting sotorasib, inform your healthcare provider and pharmacist about any allergies to sotorasib, other medications, or any ingredients in sotorasib tablets. Inquire with your pharmacist for a list of the ingredients.
Discuss all prescription, and nonprescription medications, vitamins, supplements, and herbal products you are taking or plan to take with your doctor and pharmacist. Some nonprescription or herbal products like cimetidine (Tagamet HB), esomeprazole (Nexium), famotidine (Pepcid), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), and ranitidine may interact with sotorasib. Inform your healthcare provider if you use any of these products before starting sotorasib, and do not initiate them while taking sotorasib without consulting your healthcare provider.
If you take sotorasib along with an antacid, ensure a time gap of 4 hours before or 10 hours after taking the antacid.
Notify your doctor of any history of liver disease, or lung/breathing issues, other than lung cancer.
If you are pregnant or plan to become pregnant, promptly inform your doctor. Avoid breastfeeding while receiving sotorasib and for one week after your final dose.

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