Nesina (alogliptin)


Alogliptin works by regulating the levels of insulin your body produces after eating. By inhibiting the enzyme DPP-4, alogliptin increases the amounts of two specific natural substances that help to control blood sugar. While it is not used for type 1 diabetes or diabetic ketoacidosis, Nesina is a crucial component for managing type 2 diabetes.

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Nesina, known generically as alogliptin, is an oral diabetes medication that helps control blood sugar levels. It is part of a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors and is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Additional information



● Type 2 Diabetes Mellitus: Nesina is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

Patient Guidelines

Patients prescribed Nesina should:

● Follow a specific diet and exercise program as directed by their healthcare provider.

● Regularly monitor blood glucose levels as suggested.

● Be aware of signs and symptoms of high (hyperglycemia) and low blood sugar (hypoglycemia) and know how to manage them.

● Inform their healthcare provider of their full medical history, especially if they have a history of pancreatitis, kidney disease, or if they are on dialysis.

Administration Details

How to Use Nesina:

● Oral Administration: Nesina is typically taken by mouth, once a day, with or without food.


● The dosage of Nesina is based on the patient's medical condition, kidney function, and response to treatment. It is essential to follow the healthcare provider's prescription instructions carefully.

Safety Precautions

● Pregnancy and Lactation: The safety of Nesina during pregnancy and lactation is not fully established. It should be used during these periods only if the potential benefits justify the risks.

● Pancreatitis: Patients should be advised to promptly seek medical attention if they experience severe and persistent abdominal pain.

Drug Interactions

Nesina can interact with other medications, such as:

● Insulin or Insulin Secretagogues: Careful monitoring is needed, as Nesina, when combined with these drugs, may increase the risk of hypoglycemia.

● Other Antidiabetic Drugs: Concurrent use requires close monitoring of blood sugar levels to avoid either hyperglycemia or hypoglycemia.

Side Effects

● Runny or stuffy nose and sore throat
● Headache
● Mild stomach pain

Serious Side Effects

Patients should seek immediate medical attention for:

● Severe and persistent abdominal pain, which may indicate pancreatitis
● Signs of heart failure such as shortness of breath, sudden weight gain, and swelling of the arms, legs, or feet
● Severe joint pain


● Nesina should be stored at room temperature, away from moisture and heat, in its original container.

Special Precautions

● Liver Function: While routine monitoring of liver enzymes is not required, it's important to report symptoms suggestive of hepatotoxicity such as jaundice.

● Kidney Function: Since alogliptin is excreted by the kidneys, renal function should be assessed prior to initiating therapy and periodically thereafter.

● Heart Failure: Monitor for signs and symptoms of heart failure; consider discontinuing if heart failure develops.


● An overdose of Nesina may cause severe hypoglycemia. Symptoms of overdose can include blurred vision, extreme weakness, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure. Immediate medical attention is necessary for an overdose, and treatment will involve supportive measures and glucose administration, if necessary.


28 Tablets


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