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Bromfenac, the active ingredient in Prolensa, effectively reduces inflammation by blocking the production of prostaglandins through its action on COX enzymes. By doing so, it not only minimizes ocular inflammation but also helps in managing postoperative pain, making it an invaluable tool in post-cataract surgery care.
Prolensa, known generically as bromfenac, is a potent nonsteroidal anti-inflammatory drug (NSAID) formulated explicitly for ophthalmic use. It is applied as an eye drop and is primarily used to reduce swelling and pain in the eyes post-operatively, particularly following cataract surgery. Prolensa operates by inhibiting the cyclooxygenase (COX) enzymes, crucial in synthesizing prostaglandins involved in inflammation.
| Usage: | Indications: ●Reduction of inflammation and pain after cataract surgery. Administration Guidelines Eye Drops: ●Prolensa should be administered according to a physician’s prescription, typically once daily, beginning one day before cataract surgery, continuing on the day of surgery, and maintaining through the initial phase of postoperative recovery. ●To avoid contamination, the dropper tip should not be touched to any surface, including the eye itself. ●If using other topical eye medications, there should be at least a 5-minute interval between applying each medication. Dosage Forms: ●Ophthalmic solution (eye drops) Safety Preclusions Pregnancy and Breastfeeding: ●Usage in pregnant or nursing mothers should only be undertaken if the potential benefits justify the possible risks to the fetus or infant. Data on extensive usage in this demographic is limited. Long-term Use: ●While typically not used long-term, extended use of NSAIDs may increase the risk of keratitis. Patients should be monitored for changes in vision or signs of ocular irritation. Drug Interactions: Bromfenac should be used with caution alongside other NSAIDs or steroids to avoid cumulative effects that could increase the risk of side effects. |
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| Side Effects: | ●Mild to moderate eye irritation Serious Side Effects: ●Increased risk of keratitis and corneal damage particularly with prolonged use |
| Storage: | ●Store the eye drops at room temperature, away from moisture and direct light. |
| Special Precaution | ●Patients should be instructed to administer eye drops and hygiene tips to prevent infection properly. Regular follow-up and eye exams should be scheduled to monitor the healing process and detect any unforeseen complications early. |
| Overdose | ●An overdose of eye drops is uncommon, but excessive use could amplify side effects like eye irritation, redness, or discomfort. In such cases, it's advisable to consult with a healthcare professional promptly. |
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