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Aliskiren is a medication used alone or in combination with others to treat high blood pressure. It belongs to the direct renin inhibitors class and works by reducing natural chemicals that constrict blood vessels, promoting their relaxation and improving blood pumping by the heart. Uncontrolled high blood pressure can lead to severe damage in various organs such as the brain, heart, blood vessels, kidneys, and more, potentially resulting in heart disease, heart attack, heart failure, stroke, kidney failure, vision loss, and other health issues.

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Description

Aliskiren is a medication used alone or in combination with others to treat high blood pressure. It belongs to the direct renin inhibitors class and works by reducing natural chemicals that constrict blood vessels, promoting their relaxation and improving blood pumping by the heart. Uncontrolled high blood pressure can lead to severe damage in various organs such as the brain, heart, blood vessels, kidneys, and more, potentially resulting in heart disease, heart attack, heart failure, stroke, kidney failure, vision loss, and other health issues. Alongside medication, lifestyle changes like a low-fat, low-salt diet, maintaining a healthy weight, regular exercise, non-smoking, and moderate alcohol consumption are essential for managing blood pressure.

Additional information

Usage

Usage
Aliskiren is available in tablet form for oral administration. Typically, it is taken once a day, and you can choose to take it with or without food consistently. It's important to maintain a consistent schedule, taking aliskiren at roughly the same time each day. Carefully follow the instructions on your prescription label, and if there's any aspect you're unsure about, consult your doctor or pharmacist for clarification. Adhere to your doctor's prescribed dosage – do not exceed or reduce it, and avoid taking it more frequently than instructed. Your doctor may initiate treatment with a low aliskiren dose and might adjust it after a minimum of two weeks of use. It's crucial to understand that aliskiren manages high blood pressure but does not provide a cure. Therefore, continue taking it even if you feel well, and do not discontinue its use without consulting your doctor. You can request the manufacturer's patient information from your pharmacist or doctor for additional details.

Side Effects

Side Effects
Aliskiren may lead to certain side effects. If you encounter any of these symptoms and they persist or worsen, promptly inform your doctor:
• Diarrhea
• Stomach pain
• Heartburn
• Cough
• Rash
• Dizziness
• Headache
• Back pain
However, some side effects can be severe. In such cases, cease aliskiren use and immediately contact your doctor or seek emergency medical assistance if you experience any of the following:
• Lightheadedness and fainting
• Edema or swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs may occur.
• Blisters or peeling skin
• Hoarseness
• Difficulty swallowing or breathing
• Seizure
• Slow, weak, or irregular heartbeats
Aliskiren may also induce other side effects. Should you encounter any unusual problems while taking this medication, consult your doctor for guidance.

Storage

Storage
To ensure the proper storage and disposal of this medication, please follow these guidelines:
• Keep it in the original container, securely closed, and out of children's reach.
• Store it at room temperature, away from excessive heat and moisture (avoid bathroom storage).
• Do not remove any desiccant (drying agent) provided in the bottle.
• Dispose of unneeded medication carefully to prevent access by pets, children, or others.
• Refrain from flushing this medication down the toilet, as it may harm the environment.
• Instead, utilize a medicine take-back program for proper disposal.
• Contact your pharmacist or local garbage/recycling department to learn about available take-back programs.

Precaution

Precautions
Before starting aliskiren, consider the following:
• Inform your doctor and pharmacist about any allergies to aliskiren, ACE inhibitors, or other medications, including the ingredients in aliskiren tablets.
• If you have diabetes and are taking an ARB or an ACE inhibitor, notify your doctor, as aliskiren may not be suitable for you.
• Share a complete list of all prescription, non-prescription, vitamin, supplement, and herbal products you are taking or planning to take, including medications for heart disease, high blood pressure, and other conditions.
• If you have a history of diabetes, seizures, heart attack, heart failure, or kidney disease, inform your doctor.
• If you are pregnant or nursing, avoid breastfeeding during aliskiren treatment.
• Be aware that conditions like diarrhea, vomiting, dehydration, and excessive sweating can lead to low blood pressure, resulting in lightheadedness and fainting. Report these symptoms to your doctor during treatment.

Warning

Warning
Do not use aliskiren if you are pregnant. In the event that you become pregnant while using aliskiren, promptly contact your doctor. Aliskiren has the potential to cause harm to the developing fetus.

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