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Seroquel is an oral medication that comes in tablet form. It is believed to exert its therapeutic effects through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptor antagonism. Seroquel is recognized for its sedative properties and ability to improve mood, thoughts, and behavior in psychiatric conditions.
Seroquel, generically known as quetiapine fumarate, is a prescription medication predominantly used for the treatment of certain mental health conditions, including schizophrenia, bipolar disorder, and as an adjunct treatment for major depressive disorder. It belongs to a class of drugs called atypical antipsychotics and works by altering the actions of chemicals in the brain.
| Usage | Indications: ● Treatment of schizophrenia in adults and adolescents (13-17 years old). ● Short-term treatment of acute manic episodes associated with bipolar I disorder as monotherapy or in combination with mood stabilizers in adults and pediatric patients (10-17 years old). ● Treatment of bipolar depression and as add-on therapy for major depressive disorder in adults. Administration Guidelines: ● Seroquel should be taken orally, with or without food. ● The dosing regimen will depend on the condition being treated and the individual patient's response to therapy. ● It's important to follow physician instructions and not to adjust the dose or frequency without professional guidance. Dosage Forms: ● Seroquel tablets are available in various strengths, from 25 mg to 400 mg. ● Seroquel XR (extended-release) tablets are also available for once-daily dosing and range from 50 mg to 400 mg. Safety Preclusions Pregnancy and Breastfeeding: ● The potential risks of taking Seroquel during pregnancy should be weighed against the benefits. It should only be used when necessary and if the potential benefit justifies the potential risk to the fetus. ● Caution is advised when Seroquel is administered to breastfeeding women, as it is not known if quetiapine is excreted in human milk. Long-term Use: ● Patients on long-term Seroquel therapy should undergo regular assessments to monitor efficacy and side effects, with adjustments made as necessary. Drug Interactions: ● Caution should be advised when taken with other central nervous system depressants and substances that can affect the metabolism of quetiapine. |
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| Side Effects | ● Drowsiness, dizziness, and a feeling of sedation. Serious Side Effects: ● An increased risk of suicidal thoughts and behaviors in adolescents and young adults. |
| Storage | ● Seroquel should be stored at room temperature, in a dry place away from light. ● Keep the medication in its original packaging until use, and keep it out of reach of children and pets. |
| Special Precautions | ● Seroquel should not be stopped suddenly without the guidance of a healthcare provider, as this may cause withdrawal symptoms. ● Regular monitoring for blood glucose, lipid levels, and weight is advised due to metabolic side effects. |
| Overdose | ● An overdose of Seroquel can be serious and may lead to symptoms such as extreme drowsiness, fainting, and rapid heart rate. ● In case of an overdose, seek immediate medical attention. Treatment of overdose is supportive and symptomatic. |
| MG | 25 MG, 100 MG, 200 MG, 300 MG |
| Tablets | 100 Tablets |
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