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Soriatane is an oral medication available in capsule form. It is beneficial for adults who suffer from severe psoriasis, especially when other treatments have not been effective. While not a cure for psoriasis, Soriatane can significantly control the symptoms and provide relief from the chronic, often painful condition.
Soriatane, with its active ingredient acitretin, is a systemic retinoid medication primarily used to treat severe psoriasis and other skin disorders. It works by regulating the growth and differentiation of skin cells, effectively reducing the scaling and thickness associated with psoriasis, thus improving the appearance and texture of the skin.
| Usage | Indications: ● Treatment of severe psoriasis, including plaque psoriasis, pustular psoriasis, and erythrodermic psoriasis. ● Management of other severe skin disorders as determined by a healthcare provider. Administration Guidelines: ● Dosage: The dosage of Soriatane varies depending on the severity and type of skin condition, as well as the patient's response to the medication. Dosage adjustments may be necessary to find the optimal therapeutic effect with minimal side effects. ● Method of Administration: Administered orally, typically taken once daily with the main meal to enhance absorption. ● Soriatane is generally recommended for short-term use, although some patients might need longer therapy under close doctor supervision. Dosage Forms: ● Capsules: Soriatane is available in capsule form to be taken orally, facilitating ease of use for ongoing management of psoriasis. Safety Preclusions Pregnancy and Breastfeeding: ● Soriatane is contraindicated during pregnancy and in women of childbearing potential who do not use reliable contraception during and for three years after the treatment due to the high risk of severe birth defects. ● Women must use effective contraception during treatment and continue it for three years after stopping treatment due to the drug's long half-life. Long-term Use: ● Long-term use of Soriatane can cause potential side effects such as liver damage and increased levels of blood fats. Regular blood tests are necessary to monitor liver function and lipid levels. ● Patients should also monitor for signs of mood changes or depressive symptoms. Drug Interactions: ● Caution is advised when used with other medications, particularly those metabolized by the liver or other drugs known to increase the toxicity of retinoids, such as tetracyclines. |
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| Side Effects | ● Common side effects include dryness of the skin, lips, and eyes, itching, scaling, peeling, and fragile skin. These are usually dose-dependent and may be managed with dose adjustments or supportive care. Serious Side Effects: ● Long-term use can lead to liver damage, hyperostosis (excessive bone growth), and high blood lipid levels. ● Soriatane can also cause depression and other mood changes. Immediate medical attention is required if patients experience significant mood alterations or other psychiatric symptoms. |
| Storage | ● Store capsules in a tightly sealed container away from light and moisture at room temperature. ● Keep the medication out of reach of children and pets to avoid accidental ingestion. |
| Special Precautions | ● Due to its teratogenic effects, stringent birth control measures and pregnancy tests are mandatory for women of childbearing potential. ● Avoid alcohol consumption during treatment as it can increase the risk of side effects. |
| Overdose | ● Symptoms of overdose might include headache, dizziness, abdominal pain, and peeling of the skin. Overdose can be serious, requiring immediate medical evaluation and supportive care to manage symptoms effectively. |
| MG | 25 MG, 10 MG |
| Capsules | 30 Capsules |
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