Spironolactone

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Spironolactone comes in tablet form for oral consumption. The medication is a synthetic 17-lactone drug, which is a structural analogue of aldosterone. It exhibits both diuretic and anti-androgen properties, making it versatile for managing multiple conditions associated with abnormal aldosterone levels in the body.

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100 MG

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SKU: N/A Category: Medications

Description

Spironolactone contains the active ingredient spironolactone, a potassium-sparing diuretic and anti-androgen. It is primarily used to treat conditions such as heart failure, hypertension, certain types of edema, and hyperaldosteronism. It has additional off-label uses for hirsutism, polycystic ovary syndrome (PCOS), and acne due to its anti-androgen effects. Spironolactone helps eliminate excess fluid from the body without causing potassium loss and blocks the action of male hormones that can contribute to conditions like hirsutism and acne.

Additional information

Usage	Indications: ● Management of primary hyperaldosteronism. ● Use as an adjunct in the treatment of congestive heart failure, cirrhosis of the liver accompanied by edema and/or ascites, nephrotic syndrome, and hypertension. ● Prevention of hypokalemia or treatment of hypokalemia when other measures are considered inappropriate or inadequate. ● Off-label use for acne vulgaris, hirsutism, and PCOS-related symptoms. Administration Guidelines: Dosage: ● The dosage varies by indication but typically starts at 25-100 mg daily. The dose may be adjusted based on therapeutic response and the presence of side effects. Method of Administration: ● Oral administration is the intended route for Spironolactone. It can be taken with or without food. Dosage Form: ● Tablets are the common form of Spironolactone, with various strengths available, including 25 mg, 50 mg, and 100 mg. Safety Preclusions Pregnancy and Breastfeeding: ● Spironolactone is classified under FDA pregnancy category C and should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown if spironolactone is excreted in human milk; therefore, caution should be exercised when administered to nursing mothers. Long-term Use: ● Continuous long-term use of Spironolactone requires monitoring of serum electrolytes regularly due to the risk of hyperkalemia and other electrolyte imbalances. Drug Interactions: ● Spironolactone has the potential to interact with various drugs, including
Side Effects	● Hyperkalemia ● Gastrointestinal disturbances ● Dizziness ● Rash Serious Side Effects: ● Severe electrolyte disturbances ● Hepatic dysfunction ● Allergic reactions, including anaphylaxis and severe skin reactions.
Storage	● Tablets should be stored at room temperature, between 20-25°C (68-77°F). Keep the medication away from excessive light, moisture, and the reach of children.
Special Precautions	● Careful consideration should be given to individuals with impaired renal function or diabetes mellitus. Regular monitoring of electrolytes, particularly potassium, and renal function is recommended.
Overdose	● Overdose symptoms might include dizziness, confusion, nausea, vomiting, or diarrhea. Hyperkalemia can also occur, which can be life-threatening. In the event of overdose, supportive measures and treatment of electrolyte disturbances are essential. Immediate medical attention is necessary in cases of suspected overdose.
MG	25 MG, 100 MG
Tablets	100 Tablets