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Oseltamivir is available as Tamiflu in capsule form and as an oral suspension. It is typically prescribed to be taken within two days of the onset of flu symptoms or exposure to the flu virus. The treatment involves a five-day regimen for treatment purposes or a ten-day regimen for prevention. The specific dosage depends on the patient’s age and health condition.
Tamiflu, known generically as oseltamivir, is an antiviral medication that treats and prevents influenza (flu). It is effective against Influenza A and B viruses and works by inhibiting the neuraminidase enzyme, which helps the flu virus to spread within the body. Taking Tamiflu can reduce the severity and duration of flu symptoms and may help prevent the flu in people who have been exposed to the virus but aren’t yet ill.
| Usage | Indications: ● Tamiflu is indicated for treating influenza in patients who have shown symptoms of the flu for no more than 48 hours and for preventing influenza in patients one year and older who have been exposed to influenza but do not yet show symptoms. Administration Guidelines Dosage ● Adults and Children 13 years and older: 75 mg twice daily for 5 days for treatment; 75 mg once daily for 10 days for prevention. ● Children (weight-based dosing may vary): Dosage varies; typically 30 mg to 75 mg twice daily for treatment depending on body weight. Method of Administration ● Capsules: Taken orally with or without food. ● Oral Suspension: Measured and taken according to the prescribed dose using a dosing syringe or cup. Dosage Form Tamiflu is available as: ● 30 mg, 45 mg, and 75 mg capsules ● Powder for oral suspension, which once prepared, contains 6 mg per ml oseltamivir base. Safety Preclusions Pregnancy and Breastfeeding ● Tamiflu should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown whether Tamiflu is excreted in human milk; caution should be exercised when it is administered to a nursing mother. Long-term Use ● There are no known risks associated with long-term usage of Tamiflu as it is generally used only for short treatment periods. It is not intended for long-term use. Drug Interactions ● Significant drug interactions with Tamiflu include live attenuated influenza vaccine. Tamiflu may inhibit the action of the vaccine if administered within two weeks before or 48 hours after the vaccine is given. |
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| Side Effects | ● Patients may experience nausea and vomiting, headache, and pain. These side effects are generally mild to moderate and usually occur early in the treatment. Serious Side Effects ● Rarely, severe allergic reactions, skin reactions, or neuropsychiatric events such as seizures, delirium, and abnormal behavior have been reported. |
| Storage | ● Tamiflu capsules and oral suspension should be stored at room temperature, 15°C to 30°C (59°F to 86°F). The oral suspension should be used within 17 days of preparation or as indicated on the label. |
| Special Precautions | ● Tamiflu should not be used as a substitute for the flu vaccine. The best way to prevent the flu is by getting vaccinated each year. Furthermore, safety and efficacy have not been established in children under one year of age. |
| Overdose | ● Symptoms of overdose may include nausea and vomiting. Standard supportive treatment should be applied in the event of an overdose. |
| MG | 30 Mg, 45 MG, 75 MG |
| Capsules | 10 Capsules |
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