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Xtandi (Enzalutamide)

$4,787.00

Xtandi, also known by its generic name enzalutamide, is a prescription medication primarily indicated for the treatment of advanced prostate cancer. This type of cancer often develops resistance to conventional hormone therapy, necessitating alternative approaches.

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Description

Xtandi, also known by its generic name enzalutamide, is a prescription medication primarily indicated for the treatment of advanced prostate cancer. This type of cancer often develops resistance to conventional hormone therapy, necessitating alternative approaches. Xtandi falls under the category of androgen receptor inhibitors, operating by targeting and obstructing the action of androgens – male hormones that stimulate the growth of prostate cancer cells.

This medication is meticulously crafted to address cases of metastatic castration-resistant prostate cancer (mCRPC). This advanced stage emerges when cancer cells persist in growing despite reduced testosterone levels, a hormone typically suppressed in prostate cancer treatment. Xtandi emerges as a beacon of hope for those confronted with mCRPC, offering an efficacious avenue to manage the disease’s advancement.

Xtandi’s effectiveness hinges on its capacity to disrupt the androgen signaling pathway. Prostate cancer cells thrive on androgens, which invigorate their growth. Xtandi functions by binding to androgen receptors on these cells, preventing androgens from attaching and thus impeding the signals that propel cancer cell growth. This targeted intervention curbs the cancer’s capacity to spread and effectively moderates its progression.

Additional information

Usage

Usage
-Enzalutamide is administered in capsule form for oral consumption. It's typically taken once daily, either with or without food, around the same time each day. Adhere closely to your prescription label instructions and seek clarification from your doctor or pharmacist on any unclear aspects. Ensure you take enzalutamide precisely as directed; avoid altering the dosage or frequency without your doctor's guidance. Swallow the capsules whole, refraining from chewing, dissolving, or opening them.
Should you encounter severe side effects during treatment, your doctor might advise a temporary halt or dosage reduction. Open communication about your well-being during enzalutamide treatment is essential.
If your doctor has also prescribed medications like degarelix (Firmagon), goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron), or triptorelin (Trelstar) to manage your prostate cancer, continue this treatment alongside enzalutamide. Even if you feel well, maintain enzalutamide consumption, and refrain from discontinuing without consulting your doctor.
For more information, request a copy of the manufacturer's patient information from your pharmacist or doctor.

Side Effects

Side Effects
Enzalutamide might result in side effects. Notify your doctor if any of these symptoms are severe or persist:
• Weakness
• Fatigue
• Joint discomfort
• Muscle weakness or stiffness
• Headache
• Dizziness
• Burning, numbness, or tingling in arms, hands, or feet
• Reduced touch sensation or sensation ability
• Hot flashes
• Sleep difficulties
• Anxiety
• Memory, concentration, or cognitive challenges
• Diarrhea
• Itching
• Dry skin
• Nosebleeds
• Frequent urination
Certain side effects require immediate attention. If you experience:
• Seizures
• Inflammation in arms, legs, hands, or feet
• Back and/or leg pain
• Tingling or loss of sensation in buttocks or legs
• Urination or bowel control issues
• Breathing difficulties
• Falling
• Hallucinations (seeing or hearing things not present)
• Pink or red urine
Notify your doctor urgently or seek emergency medical care.
Enzalutamide may lead to other side effects. Contact your doctor if you encounter any unusual issues during medication use.

Storage

Storage
-Store this medication in its original container, securely closed, and out of children's reach. Keep it at room temperature, avoiding excess heat and moisture (not in the bathroom). Dispose of unused medication safely to prevent accidental ingestion by pets, children, or others. Do not flush down the toilet. Explore medicine take-back programs via your pharmacist or local garbage/recycling department. Shield medication from children's view and access. Many containers, like weekly pill organizers or those for eye drops, creams, patches, and inhalers, lack child-resistant features. Always lock safety caps and place medication in an inaccessible spot, up and away from children's reach.

Precautions

Precautions
Before beginning Xtandi (Enzalutamide):

– Notify your doctor and pharmacist of any allergies to enzalutamide, other medications, or ingredients in enzalutamide capsules. Consult the manufacturer's patient information or ask your pharmacist for the ingredient list.
– Inform your doctor and pharmacist about prescribed and over-the-counter medications, vitamins, and supplements you take or plan to take. Especially mention anticoagulants like warfarin, bosentan, carbamazepine, cyclosporine, dihydroergotamine, efavirenz, ergotamine, etravirine, fentanyl, gemfibrozil, itraconazole, omeprazole, midazolam, modafinil, nafcillin, narcotic pain medications, phenobarbital, phenytoin, pimozide, quinidine, rifabutin, rifampin, rifapentine, sirolimus, and tacrolimus. Your doctor may need to adjust your medication doses or monitor for side effects. Enzalutamide can interact with numerous other medications, so inform your doctor about all your medications, even if not on this list.
– Disclose any herbal products you use, especially St. John's wort.
– Report any history of seizures, brain injury, brain tumor, arteriovenous malformation, stroke, or ministroke.
– Note that enzalutamide is only intended for men. Pregnant or breastfeeding women should avoid this medication, as it could harm the fetus. Pregnant women who take enzalutamide should contact their doctor promptly.
– If your partner is pregnant, use condoms during treatment and for three months afterward. If pregnancy is a possibility, use both condoms and another form of birth control during treatment and for three months after.
– Inform healthcare providers about enzalutamide use before any surgery, including dental procedures.
– Recognize that enzalutamide might trigger seizures. Avoid driving or operating machinery until you understand its effects on you.

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