What is Frontline Plus? | Better You RX

What is Frontline Plus?

Frontline Plus is indicated for the treatment and prevention of fleas (Ctenocephalides sp.) on dogs and cats, the control of ticks (paralysis tick and brown dog tick), and the control of biting lice on dogs.

What are Frontline Plus’s active chemicals, and how do they function?

Two active compounds are present in Frontline Plus. Fipronil, an insect neurotoxin, inhibits the transmission of nerve signals through the nervous system of fleas, ticks, and louse larvae. As a result, the parasite is rendered helpless and dies. A growth regulator for insects is (S)-methoprene. This active component obstructs the insect’s growth and development by acting like an insect hormone. It can stop the flea’s natural molting and egg-hatching processes.

How often should I apply Frontline Plus?

Frontline Plus is applied topically to the skin every four weeks to break the flea life cycle. Frontline Plus ensures that fleas that climb onto your pet cease feeding, become paralyzed, and eventually die by doing this. 

It needs to be applied every two weeks to dogs to control paralysis ticks. A monthly spray will control brown dog ticks.

How old can people use Frontline Plus?

From the age of eight weeks, Frontline Plus can be used safely on dogs and puppies.

Should pets with long and short hair receive different treatments with Frontline Plus?

Simple: No is the response. In both long-haired and short-haired breeds, Frontline Plus penetrates the oily layer of the dog’s or cat’s skin in exactly the same way. However, you must use the right product for your dog or cat based on its weight to give them the finest treatment possible.

Warning: FRONTLINE Plus for Dogs & Puppies

For the quick, efficient, and convenient treatment and control of fleas, ticks, and chewing lice in dogs and pups, turn to FRONTLINE® PLUS FOR DOGS.

  • Prevents and eliminates infestations
  • Destroys flea adults, eggs, and larvae.
  • Stops the development of all flea life stages (eggs, larvae, and pupae)
  • Eliminates fleas that could result in flea allergy dermatitis.
  • Kills all stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may spread Lyme disease).
  • Stops and manages re-infestations
  • Quickly eradicates chewing lice infestations
  • Supports the management of sarcoptic mange infestations
  • May also be applied to breeding, gestating, and nursing bitches.
  • Fast-acting
  • Long-lasting
  • Waterproof
  • They are easy to utilize.

Fipronil and the insect growth regulator (IGR) (S)-methoprene is both included in FRONTLINE® PLUS FOR DOGS. All flea life phases are successfully fought off by FRONTLINE® PLUS. In order to exert long-lasting activity against fleas, ticks, and chewing lice, fipronil accumulates in the oils of the skin and hair follicles and continues to be released from hair follicles onto the skin and coat.

Guidelines for Use

To use this product in a way that conflicts with its labeling is against federal law. Children should not apply products. Read the complete label and directions before each use to prevent injury to you and your pet. Carefully adhere to all warnings and instructions. Use only on dogs. Avoid using it on rabbits. Use is not permitted on other animals.

Apply the following to dogs or puppies (8 weeks or older) to kill fleas, all phases of brown dog ticks, American dog ticks, lone star ticks, deer ticks (which may carry Lyme disease), and chewing lice. Snap the applicator tip away from the face and torso while holding the applicator upright. Spread the applicator tip between the shoulder blades, through the animal’s hair to the skin’s surface. Apply the full contents of the applicator in one location to the animal’s skin by squeezing it. A light application to the animal’s hair should be avoided. For each treatment, only one applicator is required.

How soon does Frontline Plus start working?

Within 12 to 24 hours of application, Frontline Plus begins killing fleas, and this lasts for up to 30 days.

Frontline Plus water speed, is it?

Dogs have been used in tests to make sure Frontline Plus cannot be removed by simple rinsing or washing. It dries quickly and keeps working even after being shampooed and swimming. Prior to administering Frontline Plus, your pet is not required to be bathed; but, 48 hours after treatment, your pet should not be allowed to swim or be shampooed.

Can pets with itching skin use Frontline Plus?

Frontline Plus can be used to treat pets with flea-allergic dermatitis, also known as extremely itchy and inflamed skin caused by flea bites.

Can I take Frontline Plus throughout the year?

Since fleas are frequently a year-round issue, Frontline Plus should be treated every 4 weeks all year long.  

Can I give Frontline Plus to animals that are breastfeeding or pregnant? 

Yes, pregnant women and nursing mothers can use Frontline Plus without any problems. 

Additional Details 

NEVER administer Frontline Plus to rabbits.

Instructions for Safety 

will cause skin and eye irritation. Limit contact with the skin and eyes. If a product gets in your eyes, flush it out right away with water. After use, wash your hands.


Frontline Plus is a highly effective and versatile treatment for the prevention and control of fleas, ticks, and biting lice in dogs and cats. Its active compounds, Fipronil and (S)-methoprene, work together to target and eliminate various stages of these parasites’ life cycles. The product’s ability to penetrate the skin’s oily layer ensures long-lasting and waterproof protection for up to 30 days. Frontline Plus can be safely used on dogs and puppies from the age of eight weeks, including pregnant and nursing mothers.

Frontline Plus is easy to apply and begins working within 12 to 24 hours, providing rapid relief from flea infestations. The product’s efficacy against flea allergic dermatitis makes it suitable for pets with itching skin. Additionally, it can control various tick species, including those that may spread Lyme disease. However, it should be noted that Frontline Plus is not suitable for use on rabbits.

To maintain continuous protection, Frontline Plus should be applied every four weeks throughout the year. It is important to follow the instructions and apply the correct dosage based on the pet’s weight. While the product is water-resistant, pets should avoid swimming or being shampooed for 48 hours after application to ensure its effectiveness.

Overall, Frontline Plus offers a quick, convenient, and reliable solution for managing flea, tick, and lice infestations in dogs and cats, making it a valuable asset for pet owners seeking to keep their furry companions healthy and parasite-free. However, it is essential to read and follow the complete label and guidelines to ensure the safety and well-being of both pets and owners.

Buy Frontline Plus

If you’re to buy Frontline Plus, Better You Rx understands that pets deserve the same level of care and attention as humans. When it comes to healthcare, the well-being of our beloved pets is just as important as our own. Pets are not just animals; they become integral members of our families. Like humans, they also require medical attention and care to ensure they live healthy and fulfilling lives. Better You Rx has recognized this need and has gone beyond the conventional to provide a comprehensive range of medications not only for humans but also for our furry friends. We offer both brand name and generic equivalents. What truly sets Better You Rx apart is their dedication to catering to the medical needs of our pets.

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