Hydrocortisone, the active ingredient in Cortef, is a synthetic corticosteroid that functions similarly to cortisol, one of the body’s most important stress-response hormones. Cortisol plays a vital role in regulating metabolism, reducing inflammation, and assisting the body in stress response. By supplementing the body’s cortisol levels, Cortef aids in maintaining homeostasis when the body does not produce sufficient corticosteroids due to conditions like adrenal insufficiency or during periods of high physical stress.

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Cortef, with the generic name hydrocortisone, belongs to a class of medications known as corticosteroids, which mimic the effects of hormones naturally produced by the adrenal glands. Cortef is primarily used to treat a variety of conditions due to its potent anti-inflammatory and immunosuppressive properties. It’s commonly prescribed for conditions such as adrenal insufficiency, inflammatory disorders, allergic reactions, and certain autoimmune conditions. By closely replicating the body’s natural stress response, Cortef helps manage symptoms associated with low corticosteroid levels and mitigates overactive immune system reactions, thus providing relief from inflammation and pain.

Additional information


Indications: Cortef is indicated for the treatment of: ● Adrenal insufficiency ● Inflammatory conditions (e.g., arthritis, lupus, psoriasis) ● Severe allergic reactions ● Certain autoimmune diseases ● Asthma and other respiratory conditions To use Cortef effectively, patients should: ● Take Cortef as orally administered tablets, following the dosage and schedule prescribed by their healthcare provider. ● Understand that the dosage may be adjusted based on their condition, response to the treatment, and any side effects experienced. ● Never abruptly stop taking Cortef without medical advice due to the risk of withdrawal symptoms. Instead, the dose should be gradually tapered under medical supervision.

Side Effects

● Weight gain ● Increased appetite ● Mood swings ● Sleep disturbances ● Elevated blood sugar levels Serious side effects requiring immediate medical attention include: ● Severe stomach pain ● Sudden swelling or weight gain ● Severe depression or changes in mental state ● Visual disturbances ● Signs of infection (as Cortef can mask or worsen infections)


Store Cortef at room temperature, away from direct light, moisture, and heat. Keep the medication in its original container, and ensure it is out of reach of children and pets.

Special Precautions

Before using Cortef, inform your healthcare provider if you have: ● Any allergies to hydrocortisone or any other medications. ● A history of infections, particularly tuberculosis or fungal infections, as Cortef can weaken the immune system. ● Any medical history of diabetes, osteoporosis, thyroid disorders, or liver disease. Pregnant or nursing women should use Cortef only if clearly needed and after discussing potential risks and benefits with their healthcare provider


An overdose of Cortef can lead to symptoms such as high blood pressure, fluid retention, and potassium loss. Excessive use over an extended period increases the risk of side effects. If an overdose is suspected, or if Cortef is used more frequently than prescribed, seek medical attention immediately.


10MG, 20MG


100 Tablets


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