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Erlotinib functions as an EGFR inhibitor, targeting the tyrosine kinase domain within this receptor, which is often overactive in various forms of cancer. By blocking the activity of this domain, Erlotinib disrupts the growth and division signals in cancer cells, leading to their death and inhibiting tumor growth. This mechanism of action makes it an effective option for treating specific types of cancer with identified genetic markers for EGFR activation.
Erlotinib, marketed under the trade name Tarceva, among others, is a targeted therapy used in the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer. It is specifically designed for cancers with certain epidermal growth factor receptor (EGFR) mutations, promoting cancer cell growth. By inhibiting these receptors, Erlotinib helps slow the growth and spread of tumors. It is typically used when other cancer treatments have not been effective.
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