Furosemide

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Furosemide acts on the ascending limb of the loop of Henle in the nephrons of the kidneys. It binds to the chloride channel of the sodium-potassium-chloride co-transporter system, which results in the excretion of sodium, water, potassium, calcium, and magnesium. By increasing the amount of urine produced, Furosemide alleviates the symptoms associated with fluid retention.

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Description

Furosemide is a powerful diuretic medication commonly used to reduce excess fluid in the body caused by conditions such as heart failure, kidney disease, and cirrhosis of the liver. By promoting the production of urine, it helps to alleviate the symptoms of fluid overload, such as shortness of breath and swelling in the limbs (edema). Furosemide is part of the loop diuretic class, which works on the loop of Henle in the kidney to inhibit the reabsorption of sodium and chloride.

Additional information

Usage	Indications: Furosemide is indicated for: ● The management of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease. ● The treatment of hypertension to lower high blood pressure, which helps prevent strokes, heart attacks, and kidney problems. Patients are advised to: ● Take the medication as prescribed by a healthcare provider, usually once or twice a day. ● Take it on an empty stomach, usually in the morning, and ensure they remain well hydrated. ● Be aware that they will need to urinate frequently when taking this drug, so they should take it at a time that avoids disrupting sleep patterns. Precautions: ● Furosemide can cause electrolyte imbalances; therefore, monitoring of blood electrolytes is necessary. ● It should be used with caution in patients with pre-existing electrolyte abnormalities, diabetes, gout, or lupus. ● Hearing impairment has been reported, particularly in patients with severe renal dysfunction or hypoproteinemia and in patients receiving higher doses or rapid intravenous administration.
Side Effects	● Increased urination ● Thirst ● Muscle cramps ● Dizziness or light-headedness More serious but less common side effects requiring medical attention: ● Severe electrolyte imbalance (symptoms might include dry mouth, increased thirst, weakness, drowsiness, restlessness, muscle pains or cramps, low blood pressure, weak pulse, nausea, vomiting) ● Hearing damage or tinnitus (especially with large doses or in patients with kidney problems) ● Signs of an allergic reaction, such as rash, itching/swelling, severe dizziness, or trouble breathing
Storage	● Store Furosemide at a room temperature between 15°C to 30°C (59°F to 86°F). ● Protect it from light and moisture, and do not store it in the bathroom. ● Keep it in its original packaging, and make sure the container is tightly closed. Special Precautions Before commencing treatment with Furosemide, patients should inform their healthcare provider if: ● They have a history of kidney problems, liver problems, gout, lupus, or diabetes. ● They are taking other medications, particularly those affecting blood pressure or drugs that can cause hearing damage. ● They are pregnant or breastfeeding, as Furosemide can pass into breast milk and may harm a nursing infant.
Overdose	Symptoms of a Furosemide overdose can include dehydration, significant reduction in blood volume, electrolyte depletion, severe low blood pressure, and possibly circulatory collapse. Immediate medical attention is required, with management including rehydration and symptomatic care as needed.
MG	20 MG, 40 MG, 80 MG
Tablets	100 Tablets