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Glyburide exerts its hypoglycemic action primarily by stimulating the beta cells of the pancreatic islets of Langerhans to release insulin, thus enhancing the overall secretion of insulin from the pancreas. It is more applicable for individuals with some remaining pancreatic beta-cell function. The initiation of insulin release is dependent upon functioning beta cells in the pancreatic islets.
Glyburide, also known by its brand names, such as Diabeta and Glynase, is a medication used to manage blood sugar levels in people with type 2 diabetes mellitus. As a part of the sulfonylurea class of drugs, glyburide works by increasing the release of insulin from the pancreas. This action helps lower blood sugar levels. It is used when diet, exercise, and weight reduction have not been found to control blood sugar well enough on their own.
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