Haloperidol

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Haloperidol works primarily by blocking dopamine receptors in the brain. Dopamine is a neurotransmitter that influences mood, perception, and movement. Excess dopamine activity is associated with psychosis and other psychiatric disorders. By interfering with dopamine transmission, haloperidol can reduce psychotic symptoms, improve thinking and behavior, and provide a calming effect.

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Description

Haloperidol, commonly known by its brand name Haldol among others, is a medication used in the treatment of schizophrenia, Tourette syndrome, acute psychotic states, and delirium. It belongs to the class of antipsychotic drugs, specifically first-generation or typical antipsychotics. Haloperidol can help to control symptoms of hyperactivity, aggression, and mood swings. It is available by prescription and comes in various forms, including oral tablets, solutions, and injectables.

Additional information

Usage

Haloperidol is typically used for:

● Managing symptoms of psychotic disorders including schizophrenia
● Controlling motor and verbal tics in Tourette syndrome
● Treating acute psychotic episodes and delirium
● Reducing severe behavioral problems in children when other treatments have failed

Patients are generally advised to:

● Take haloperidol as prescribed by their healthcare provider
● Avoid sudden discontinuation of the medication without consulting a physician, as it may lead to withdrawal symptoms

Precautions:

● Haloperidol may cause extrapyramidal symptoms (movement disorders) and tardive dyskinesia (involuntary movements)
● It can cause orthostatic hypotension (sudden drop in blood pressure upon standing), leading to dizziness or fainting
● Avoid use with alcohol as it may potentiate the effects of haloperidol
● Caution should be exercised with elderly patients, particularly those with dementia-related psychosis as there is an increased risk of death

Side Effects

● Drowsiness
● Insomnia
● Headache
● Dizziness
● Extrapyramidal symptoms, such as restlessness or tremor

Serious side effects that require medical attention can include:

● Severe neurological symptoms known as neuroleptic malignant syndrome (NMS)
● Heart problems such as QT prolongation
● Severe allergic reactions
● Persistent and severe movement disorders known as tardive dyskinesia
● Blood disorders

Storage

● Store haloperidol at room temperature, away from heat, direct light, and moisture
● Keep the medication out of reach of children and pets, and preferably locked up

Special Precautions

Before taking haloperidol, it's important to inform your healthcare provider if:

● You have a history of heart disease, seizures, thyroid problems, Parkinson's disease, or any other medical conditions
● You are taking any other medications, including over-the-counter drugs and supplements, as haloperidol can interact with many substances
● You are pregnant, planning to become pregnant, or breastfeeding, as the effects of haloperidol on an unborn baby or nursing infant are not fully known

Overdose

Symptoms of haloperidol overdose can include severe drowsiness, rapid heartbeat, severe extrapyramidal symptoms, low blood pressure, and unconsciousness. In the event of an overdose, immediate medical attention is necessary. Contact emergency services or go to the nearest emergency room and provide as much information as possible about the overdose, including how much haloperidol was taken and when.

MG

0.5 MG, 1MG, 2MG, 5 MG

Tablets

100 Tablets

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