Indications:
● Long-term treatment of schizophrenia in adults, facilitating symptom management over an extended period.
● Management of bipolar disorder, including maintenance treatment of bipolar I disorder as an adjunct to lithium or divalproex.
● As add-on therapy for major depressive disorder in adults who have not adequately responded to antidepressant medications alone.
Administration Guidelines:
● Seroquel XR should be ingested whole, without crushing or chewing, to preserve the extended-release properties. It can be taken with or without food.
● The precise dosage and treatment scheme will be determined by the healthcare provider based on the patient's condition, response to treatment, and other factors. It is crucial to adhere closely to the provided instructions.
● Due to its once-daily dosing, it is recommended to take Seroquel XR at the same time each day to maintain consistent blood levels of the medication.
Dosage Forms:
● Seroquel XR is available in a range of strengths, including 50 mg, 150 mg, 200 mg, 300 mg, and 400 mg tablets, to accommodate varying therapeutic needs.
Safety Preclusions
Pregnancy and Breastfeeding:
● The use of Seroquel XR during pregnancy or lactation should be considered only if the potential benefits justify the potential risks to the fetus or infant. It is not well-established whether quetiapine is excreted in human breast milk.
Long-term Use:
● Long-term treatment with Seroquel XR necessitates a systematic evaluation of the drug's efficacy and side effect profile for the individual patient, adjusting treatment as required.
Drug Interactions:
● Combining Seroquel XR with CNS depressants, drugs affecting hepatic enzymes, or other medications that interact with dopamine and serotonin receptors should be approached with caution.
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