Seroquel Xr


Seroquel XR is an oral medication in tablet form, formulated to release the drug slowly over time, allowing for once-daily dosing. This extended-release quality provides steady medication levels in the bloodstream, contributing to enhanced convenience and adherence to treatment regimens over standard formulations. By antagonizing dopamine type 2 (D2) and serotonin type 2 (5HT2) receptors, Seroquel XR helps in reducing psychotic symptoms and stabilizing mood.

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Seroquel XR, an extended-release formulation of quetiapine fumarate, is a prescribed medication that is used to treat certain mental health disorders. It is designed for once-daily administration to manage conditions such as schizophrenia, bipolar disorder, and as an adjunctive treatment for major depressive disorder. As part of the atypical antipsychotics class, Seroquel XR works by modifying the balance of neurotransmitters in the brain, particularly targeting dopamine and serotonin receptors to alleviate symptoms of psychotic disorders and depression.

Additional information



● Long-term treatment of schizophrenia in adults, facilitating symptom management over an extended period.

● Management of bipolar disorder, including maintenance treatment of bipolar I disorder as an adjunct to lithium or divalproex.

● As add-on therapy for major depressive disorder in adults who have not adequately responded to antidepressant medications alone.

Administration Guidelines:

● Seroquel XR should be ingested whole, without crushing or chewing, to preserve the extended-release properties. It can be taken with or without food.

● The precise dosage and treatment scheme will be determined by the healthcare provider based on the patient's condition, response to treatment, and other factors. It is crucial to adhere closely to the provided instructions.

● Due to its once-daily dosing, it is recommended to take Seroquel XR at the same time each day to maintain consistent blood levels of the medication.

Dosage Forms:

● Seroquel XR is available in a range of strengths, including 50 mg, 150 mg, 200 mg, 300 mg, and 400 mg tablets, to accommodate varying therapeutic needs.

Safety Preclusions

Pregnancy and Breastfeeding:

● The use of Seroquel XR during pregnancy or lactation should be considered only if the potential benefits justify the potential risks to the fetus or infant. It is not well-established whether quetiapine is excreted in human breast milk.

Long-term Use:

● Long-term treatment with Seroquel XR necessitates a systematic evaluation of the drug's efficacy and side effect profile for the individual patient, adjusting treatment as required.

Drug Interactions:

● Combining Seroquel XR with CNS depressants, drugs affecting hepatic enzymes, or other medications that interact with dopamine and serotonin receptors should be approached with caution.

Side Effects

● Drowsiness, dizziness, and extended sedation.
● Dry mouth, constipation, and mild stomach discomfort.
● Appetite increase leading to weight gain.

Serious Side Effects:

● Risk of depression worsening and suicidal ideation, especially in younger adults.
● Development of tardive dyskinesia with long-term use.
● Metabolic side effects, including alterations in glucose and lipid profiles.


● Store the Seroquel XR tablets at room temperature, protected from moisture and light.

● Ensure the medication remains in its original packaging until ready to use, keeping it securely away from children and pets.

Special Precautions

● Abrupt discontinuation of Seroquel XR should be avoided to prevent withdrawal symptoms. Any changes in dosing should be done under medical supervision.

● Ongoing monitoring of blood sugar, lipid levels, and body weight is essential due to the potential for metabolic disturbances.


● Overdose on Seroquel XR may manifest as severe drowsiness, fainting, or an abnormal heart rate. It requires immediate medical attention, with supportive and symptomatic care being the cornerstone of treatment.


50 MG, 150 MG, 200 MG, 300 MG, 400 MG


60 Tablets


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