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Alfuzosin operates by selectively blocking alpha-1 adrenergic receptors found in the prostate and bladder base muscle. This action reduces the muscle tone in these areas, improving urine flow and reducing the symptoms associated with BPH without surgery.
Xatral, known generically as alfuzosin, is an oral medication that falls within the category of alpha-blockers. It is specifically designed for the treatment of benign prostatic hyperplasia (BPH), a condition commonly referred to as an enlarged prostate. Alfuzosin works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate and alleviating the symptoms of BPH.
| Usage | Indications: ● Benign Prostatic Hyperplasia (BPH): Alfuzosin is indicated for the treatment of BPH signs and symptoms. It improves urination in men with enlarged prostates and reduces the need for BPH-related surgery. Administration Guidelines Dosage: ● Xatral (alfuzosin) is typically 10 mg once daily, taken after the same meal each day to ensure consistent absorption and effect. Method of Administration: ● Oral: Xatral is taken by mouth immediately after a meal. Dosage Form: ● Extended-release tablet: The common form is a 10 mg extended-release tablet designed for once-daily dosing. Safety Preclusions Pregnancy and Breastfeeding: ● Alfuzosin is not indicated for use in women and, therefore, should not be used during pregnancy or breastfeeding. Drug Interactions: ● Caution is advised with other medications that lower blood pressure, strong inhibitors of CYP3A4 (such as ketoconazole), and other alpha-blockers. ● Patients should review their medications and supplements to avoid potential interactions with their healthcare provider. |
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| Side Effects | ● Dizziness Serious Side Effects: In rare cases, serious side effects may warrant immediate medical attention, including: ● Severe hypotension (low blood pressure) |
| Storage | ● Xatral should be stored at room temperature, between 15°C and 30°C (59°F and 86°F), and kept in its original packaging to protect it from moisture and light. |
| Special Precautions | ● Patients taking Xatral should be cautious about driving or operating machinery until they know how alfuzosin affects them due to the risk of dizziness or weakness. Regular follow-ups with a healthcare provider are recommended to monitor the effectiveness and any potential side effects of the treatment. |
| Overdose | ● In case of an overdose of Xatral, immediate medical attention is crucial. Overdose symptoms can include severe hypotension, dizziness, and fainting. Supportive care and symptomatic treatment are the mainstays of managing an overdose, as there is no specific antidote for alfuzosin. |
