Aliskiren is a medication used alone or in combination with others to treat high blood pressure. It belongs to the direct renin inhibitors class and works by reducing natural chemicals that constrict blood vessels, promoting their relaxation and improving blood pumping by the heart. Uncontrolled high blood pressure can lead to severe damage in various organs such as the brain, heart, blood vessels, kidneys, and more, potentially resulting in heart disease, heart attack, heart failure, stroke, kidney failure, vision loss, and other health issues.