Pramipexole’s mechanism centers on its selective stimulation of dopamine D2 and D3 receptor subtypes in the brain. This activation helps to supplement or replace the dopamine that is in short supply in the brains of individuals suffering from Parkinson’s disease or related disorders.
By doing so, Pramipexole aids in the alleviation of symptoms such as stiffness, tremors, spasms, and poor muscle control. Additionally, its effects on the dopamine system also make it effective in treating the symptoms of restless legs syndrome, providing relief from discomfort and the uncontrollable urge to move the legs.