Arthrotec is a specialized medication developed to treat signs and symptoms associated with osteoarthritis and rheumatoid arthritis, especially in patients at a higher risk of developing stomach ulcers from non-steroidal anti-inflammatory drugs (NSAIDs). Arthrotec combines two active ingredients: diclofenac sodium, an NSAID that reduces pain and inflammation, and misoprostol, a prostaglandin that helps protect the stomach lining from the erosive effects of NSAIDs. This combination addresses both the discomfort of arthritis and the gastrointestinal risks associated with NSAID therapy.

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Arthrotec’s dual-component formula provides a balanced approach to arthritis treatment. Diclofenac sodium targets the enzymes involved in prostaglandin synthesis, effectively reducing arthritis-induced pain and inflammation. Concurrently, misoprostol acts as a synthetic prostaglandin E1 analog, promoting the production of gastric mucus and bicarbonate, which are crucial for protecting the stomach lining and reducing the risk of ulceration. This synergistic action makes Arthrotec a comprehensive treatment option for those requiring long-term NSAID therapy but who are at risk for gastrointestinal complications.

Additional information


Arthrotec is intended for adult use and should be taken orally. The typical dosage is one tablet two to three times daily, depending on the physician's recommendation and the patient's condition. It is important to take Arthrotec with food to reduce the risk of stomach upset. The dosing regimen should be strictly followed as per the healthcare provider's instructions, and patients should not exceed the prescribed dosage to avoid potential adverse effects.

Side Effects

● Gastrointestinal distress, such as diarrhea, nausea, and abdominal pain ● Headache and dizziness ● Increased risk of bleeding ● Skin reactions, such as rash or itching In some cases, more severe side effects may occur, such as: ● Severe gastrointestinal bleeding or ulceration ● Cardiovascular events, such as heart attack or stroke ● Hepatic dysfunction or serious liver damage ● Anaphylactic reactions in patients with known allergies to NSAIDs


Arthrotec should be stored at room temperature, away from moisture and direct sunlight. The medication should not be exposed to high temperatures and kept in its original packaging until use. It is essential to keep Arthrotec out of reach of children and pets to prevent accidental ingestion.

Special Precautions

Before starting Arthrotec, patients should discuss their full medical history with their healthcare provider, especially regarding any history of gastrointestinal disease, heart disease, liver or kidney conditions, or known allergies to diclofenac, misoprostol, or other NSAIDs. Due to misoprostol's abortifacient properties, Arthrotec is contraindicated in pregnant women. Patients should also inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to avoid potential drug interactions.


In case of an overdose, patients may experience symptoms such as drowsiness, nausea, vomiting, or more severe gastrointestinal bleeding. Overdose requires immediate medical attention. The management of an overdose will depend on the symptoms and may involve supportive care in a hospital setting.


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