Estradiol is biologically identical to the estrogen produced by the human ovaries. It is available under various brand names and comes in multiple forms, including oral tablets, topical creams, patches, injections, and vaginal rings. Its primary function in therapy is to replace or supplement natural estrogen levels in the body, which can decline due to menopause, ovarian failure, or certain medical procedures like oophorectomy. By mimicking the action of natural estrogen, estradiol can alleviate various symptoms and conditions associated with low estrogen levels.