Medroxyprogesterone acetate mimics the action of natural progesterone, which is essential for regulating ovulation, menstrual cycles, and the stability of the uterine lining. Its mechanism involves altering the uterine lining, making it less likely to cause overgrowth and potentially abnormal bleeding. It is effective in preventing endometrial hyperplasia in postmenopausal women undergoing estrogen replacement therapy and in treating secondary amenorrhea, providing benefits in managing symptoms and reducing the risk of endometrial cancer.

SKU: N/A Category:


Medroxyprogesterone acetate, a synthetic form of the naturally occurring female hormone progesterone, is utilized in a variety of medical applications, including hormone replacement therapy and the treatment of menstrual disorders. This medication plays a crucial role in regulating ovulation and menstruation. It is commonly prescribed for conditions such as abnormal uterine bleeding, and secondary amenorrhea, and as part of menopausal hormone therapy in combination with estrogen.

Additional information



● Prevention of endometrial hyperplasia in postmenopausal women receiving estrogen therapy.
● Treatment of secondary amenorrhea.
● Management of abnormal uterine bleeding unrelated to menstrual cycle.
● Part of hormone replacement therapy (HRT) in postmenopausal women.

Patients should:

● Follow the dosing schedule as prescribed by the healthcare provider.
● Inform their healthcare provider of any pre-existing conditions such as heart disease, liver disease, or a history of stroke.
● Discuss the risks and benefits if used as part of hormone replacement therapy, particularly in the context of a personal or family history of breast cancer.
● Avoid smoking, as it may increase the risk of cardiovascular side effects.


Available in tablet form and as an injectable administered by healthcare professionals:

● Oral tablets should be taken with water or other liquids, with or without food.
● Injectable forms (including Depo-Provera for contraceptive use) are administered intramuscularly by a healthcare professional.


● Not recommended for use during pregnancy.
● May increase the risk of blood clots, stroke, and heart attack, especially in smokers and women over 35.
● Regular monitoring for signs of endometrial or breast cancer is advised in long-term use.

Drug Interactions:

● Interactions may occur with anticoagulants, other hormone therapies, and medications metabolized by liver enzymes. Always inform healthcare providers of all medications and supplements being taken.

Side Effects

● Weight gain
● Mood changes
● Headaches
● Abdominal pain or discomfort
● Breast tenderness

Serious side effects requiring immediate medical attention:

● Vision changes or eye pain
● Severe headaches
● Swelling or pain in the legs
● Shortness of breath
● Signs of a stroke (sudden numbness, confusion, trouble speaking)


● Store tablets at room temperature away from moisture and heat. Injectable forms should be stored according to the manufacturer's instructions, typically under refrigeration.

Special Precautions

● Detailed medical history and physical exams, periodic follow-ups are recommended before starting therapy.
● Effect on bone density for long-term use of injectable forms (e.g., Depo-Provera) warrants caution, particularly in adolescents and young women


● Symptoms of overdose may include nausea, vomiting, drowsiness, or vaginal bleeding. In cases of overdose, contact a healthcare provider or poison control center immediately for guidance.


There are no reviews yet.

Be the first to review “Medroxy”

Your email address will not be published. Required fields are marked *