Indications:
● Prevention of Angina Pectoris: Nitro-Dur is extensively prescribed to prevent angina pectoris. It does not provide immediate relief from acute angina attacks but is used as part of a comprehensive preventative cardiac care program.
Patient Guidelines
● Patients prescribed with Nitro-Dur should adhere to the following usage guidelines:
● Start using Nitro-Dur patches as instructed by a healthcare provider, usually one patch applied each day.
● Apply the patch on a clean, dry, and hairless area of skin, preferably on the upper body or upper arm.
● Remove the patch after 12-14 hours to allow a nitrate-free interval of 10-12 hours each day, typically during nighttime. This regimen helps prevent the development of tolerance to nitrates.
● Rotate patch application sites daily to avoid skin irritation.
Administration Details
How to Use Nitro-Dur:
● Transdermal Patch: Nitro-Dur is available as a skin patch that releases nitroglycerin over a specified period, providing a steady dose that aids in the prevention of angina.
Dosage Forms:
● The patch comes in various dosage strengths, such as 0.2 mg/hr, 0.4 mg/hr, and 0.6 mg/hr, allowing customization of treatment according to individual patient needs and severity of symptoms.
Dosage:
● The specific dosage and treatment schedule depend on the severity of the condition and the patient's overall health profile. A typical dosage involves daily applications of the patch following a strict schedule to maintain optimal nitroglycerin levels in the bloodstream.
Safety Precautions
● Pregnancy and Lactation: Consultation with a healthcare provider is crucial as the effects of nitroglycerin on unborn babies or nursing infants are not well-established.
● Hypotension: Patients with low blood pressure should use Nitro-Dur cautiously, as further reduction in blood pressure may occur leading to possible complications.
Drug Interactions
● Nitro-Dur can interact with other medications such as phosphodiesterase inhibitors (used to treat erectile dysfunction) and certain antihypertensive drugs, potentially leading to severe drops in blood pressure. It is essential to inform the healthcare provider of all medications currently being taken.
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