Nitrofurantoin

Name: Prescription Medication Drugs Online | Better You Rx
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$56.95 – $82.95

Nitrofurantoin is a widely used antibiotic that plays a critical role in the treatment of urinary tract infections (UTIs). It is specifically characterized by its action against a broad spectrum of bacteria that commonly cause infections in the urinary system. Nitrofurantoin is favored for its high urinary concentrations, excellent tissue penetration in the bladder, and minimal systemic absorption, which reduces the potential for side effects and antibiotic resistance. The medication provides an effective means for both treatment and prevention of uncomplicated cystitis and is a preferred choice for its targeted action.

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Usage	Indications: ● Treatment and Prevention of UTIs: Nitrofurantoin is primarily indicated for the treatment and prevention of acute cystitis, often caused by bacteria such as Escherichia coli and Staphylococcus saprophyticus. It can also be used in a prophylactic manner to prevent recurrent urinary tract infections in patients with a history of frequent UTIs. Patient Guidelines Patients prescribed Nitrofurantoin should be aware of the following: ● Only take this medication under the prescription and supervision of a healthcare provider. ● Usually administered orally in capsule or liquid suspension form. ● Should be taken with food to enhance absorption and reduce the risk of gastrointestinal upset. ● Adequate hydration should be maintained throughout the course of treatment. ● Complete the full course of treatment even if symptoms improve, to prevent bacterial resistance and recurrence of infection. Administration Details How to Use Nitrofurantoin: ● Oral Administration: Nitrofurantoin is taken orally with or without food, although taking it with food or milk may increase its efficacy and reduce stomach upset. Dosage Forms: ● Available in macrocrystalline form (Macrodantin, Furadantin) and a monohydrate/macrocrystals form (Macrobid), with the latter often preferred for its twice-daily dosing. Dosage: ● Dosage is based on the patient's medical condition and response to therapy. Common regimens include 50 to 100 mg four times a day for seven days for treatment, or a single daily dose for prophylaxis. Safety Precautions ● Contraindications: Nitrofurantoin is contraindicated in patients with severe renal impairment, known hypersensitivity to the drug, and in infants under one month of age. ● Pregnancy and Lactation: Generally considered safe during pregnancy, but risk-benefit must be considered, especially at term. Drug Interactions Nitrofurantoin may interact with the following: ● Antacids containing magnesium trisilicate ● Probenecid and sulfinpyrazone ● Quinolone antibiotics ● Patients should inform their healthcare provider about all the medications they are taking.
Side Effects	● Nausea ● Vomiting ● Loss of appetite ● Diarrhea ● Headaches Serious Side Effects Less common but more serious side effects requiring medical attention include: ● Lung inflammation ● Hepatic toxicity ● Peripheral neuropathy ● Hemolytic anemia in patients with G6PD deficiency
Storage	● Store at room temperature away from light and moisture. Do not store in the bathroom.
Special Precautions	● Renal Function: Due to excretion through the kidneys and potential nephrotoxic effects, renal function should be monitored before initiation and during therapy. ● Long-Term Use: Prolonged use may lead to fungal or bacterial superinfection, including C. difficile-associated diarrhea. Regular monitoring and reassessment of antibiotic efficacy are recommended for long-term use. ● Hemolysis Risk: Patients with G6PD deficiency have an increased risk of hemolysis. They should not receive Nitrofurantoin unless deemed necessary and monitoring should be considered.
Overdose	● An overdose of Nitrofurantoin may present with vomiting, which can be treated symptomatically. Dialysis is not effective due to its high tissue binding and low plasma concentrations. Patients suspected of an overdose should seek emergency medical intervention.
MG	50 MG, 100 MG
Tablets	100 Tablets