Zovirax Cream 5% 5g


Acyclovir, the active component in Zovirax Cream, is a synthetic nucleoside analogue targeting viral replication. When applied to lesions, the drug interferes with the viral DNA polymerase enzyme, stopping the virus from multiplying. This targeted approach allows for the effective management of herpes symptoms directly at their source.



Zovirax Cream contains the antiviral acyclovir, which is effective against herpes simplex viruses. Specifically formulated as a topical preparation, it treats skin infections caused by the herpes virus, including cold sores (herpes labialis) and genital herpes. By inhibiting viral DNA synthesis, it helps decrease the severity and duration of these outbreaks.

Additional information



● Cold Sores (Herpes Labialis): Zovirax Cream is indicated for treating cold sores around the mouth caused by herpes simplex virus type 1 (HSV-1).

● Genital Herpes: While less common, it can be used off-label for treating genital herpes lesions, targeting herpes simplex type 2 (HSV-2).

Administration Guidelines

Dosage and Application:

● Cold Sores: For adults and adolescents, apply a layer of Zovirax Cream to the affected area 5 times daily for 4 days. Treatment should begin as early as possible after the start of an infection, ideally during the tingling phase before blisters appear.

● The precise amount of cream to be applied and the duration of treatment for genital herpes should follow a doctor’s recommendation.

Method of Administration:

● Topical Cream: Zovirax Cream is applied directly to herpes sores on the skin. It's important to wash hands before and after applying the cream to prevent spreading the infection.

Safety Preclusions

Pregnancy and Breastfeeding:

● Considered safe for use during pregnancy and breastfeeding, Zovirax Cream should still be used under the guidance of a healthcare provider to ensure the benefits outweigh any potential risks.

Drug Interactions:

● Due to their topical application, topical treatments interact minimally with systemic medications. However, patients should inform their healthcare provider about other topical treatments.

Side Effects

● Mild pain, burning, or stinging upon application
● Itching
● Redness at the application site

Serious Side Effects:

● Allergic reactions are rare but can occur. Symptoms include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing.


● Store Zovirax Cream at room temperature, between 68°F to 77°F (20°C to 25°C), away from light and moisture.

● Keep the tube tightly closed when not in use.

● Do not freeze the cream.

Special Precautions

● Avoid applying Zovirax Cream to or near the eyes, as it may irritate them. If the product gets into the eyes, rinse thoroughly with water.

● Apply only to skin surfaces affected by the herpes virus. The cream is not intended for application on mucous membranes such as the mouth, inside the vagina, or in the eyes.

● Zovirax Cream should not be seen as preventing herpes transmission to others.


● Topical overdose is unlikely to occur or produce severe symptoms. However, if Zoviracy Cream is ingested, seek medical attention or contact a Poison Control Center immediately.


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