Duloxetine is prescribed to alleviate symptoms of depression and generalized anxiety disorder (GAD), characterized by persistent excessive worry and tension lasting for six months or more, disrupting daily life. Additionally, it’s used to manage discomfort and tingling resulting from diabetic neuropathy (nerve damage in diabetes patients) and fibromyalgia (a chronic condition associated with pain, muscle stiffness, tenderness, fatigue, and sleep disturbances).