Combining Trulicity and Metformin: A Comprehensive Guide | Better You Rx

Trulicity and Metformin: Taking The Two Together

Many disorders can now be treated thanks to developments in medicine and healthcare, which give people better access to management and treatment alternatives.

One of these illnesses is diabetes, to some extent. Its management methods have seen substantial improvements over time. As a result, the disease and its related effects are now better understood.

In the modern era, people can easily control their blood sugar levels thanks to widely accessible medications. In this regard, two extremely well-liked diabetes medications used to treat type 2 diabetes are Trulicity and Metformin. They are also used together in some cases.


Trulicity initially appeared on the market in 2014, but metformin had long been the primary treatment for type 2 diabetes. It is a brand name for the drug dulaglutide, which is a generic version of it. 

In people with type 2 diabetes who are at risk for cardiovascular disorders, Trulicity is also useful in preventing major heart health problems. Trulicity is typically not the initial treatment option for type 2 diabetes. Instead, it is advised to take it along with another diabetes medicine. For instance, some people combine the medications Trulicity and Metformin. In the section that follows, we shall examine this choice.

What’s the Process of Trulicity?

We previously reported that the generic drug dulaglutide, sold under the brand name Trulicity, is a member of the class of drugs known as GLP-1 receptor agonists and is related to the well-known medication Ozempic

According to clinical studies, Trulicity may be able to reduce HbA1C levels by as much as 1.5%.

By encouraging the body to secrete more insulin and blocking the liver’s ability to produce glucose, the medications in this class can lower blood sugar levels in the body. With less chance of hypoglycemia, Trulicity provides a non-insulin-based injectable solution for controlling the body’s blood sugar levels.

Trulicity is not a substitute drug for type 1 diabetes, hence it must not be used to treat type 1 diabetes.

What is your opinion of Trulicity?

It is best to speak with your medical director to find out and prescribe the Trulicity dose strength that would be most effective for you. The specifics of the recommended dosage will be provided.

Trulicity is often given intramuscularly with injections. Initially, 0.75 mg injections administered twice a week are advised. Trulicity can also be delivered by single-dose pens with varied strengths, including 0.75mg, 1.5mg, 3mg, and 4.5mg per 0.5 ml. These pens function similarly to Saxenda pens and are often available in injection form.

The first recommended dose is 0.75 mg, however, it may be gradually raised for improved control of the body’s glycemic levels. Raising the dosage requires caution, though, as a greater dose of Trulicity might cause unpleasant side effects including nausea.

Please be aware that this is the recommended dosage; each patient will receive a personalized dosing schedule from their doctor or other healthcare provider.

Side Effects of Trulicity

Trulicity and Metformin both have some potential adverse effects. The most frequent side effect of Trulicity, as was discussed in the previous section, is nausea. One dose may cause nausea in some people for two to three days. With time, the nausea goes away on its own. If nausea is persistent, eating more frequent smaller meals and bland foods may help.

Trulicity also has other adverse effects including decreased appetite, nausea, diarrhea, and discomfort in the abdomen. Additionally, the injection site could occasionally itch, swell, or hurt.

Trulicity precautions

A thorough description and usage instructions are included with the medication. In the presence of some medical conditions, Trulicity is not recommended. For instance, Trulicity produced thyroid cancers in rats or mice according to clinical trials. If you have a family history of thyroid carcinoma, it would be advisable to avoid taking the drug even if there is no proof that it would affect humans in the same way.

Similar to this, Trulicity use has also been connected to pancreatitis, gastrointestinal problems, and potential kidney damage.

Utilizing Trulicity also helps individuals lose weight. But if you want to use Trulicity for weight loss, it would be wise to eat healthily. 

Trulicity and Metformin have both been investigated for use by women who are pregnant or nursing. There is a chance that Trulicity could harm the fetus during pregnancy, even though there is little information on this. Therefore, it is recommended that expecting mothers only use Trulicity when the advantages outweigh the hazards. Anyhow, a healthcare supervisor should always be consulted for advice.

Taking Metformin and Trulicity simultaneously

Trulicity and Metformin combined are generally regarded as safe for treating type 2 diabetes. In some cases, people might need to take the two medications simultaneously in order to achieve the ideal blood sugar level for their bodies. However, a doctor’s consent is required for their combination use.

If you can use Trulicity and Metformin together, your healthcare manager will consider your health history, medical issues, and profile. Incorporating Trulicity into your treatment plan may be beneficial if you have type 2 diabetes and are currently taking Metformin but are unable to control your blood glucose levels (despite regular doses coupled with exercise and diet).

For some people, taking Trulicity makes Metformin work better. Trulicity increases the body’s ability to produce insulin, whilst Metformin lowers blood sugar levels by reducing the production of glucose.

What does it mean when we claim that Trulicity and Metformin can be taken concurrently? It means that although you might take Trulicity once a week as per the recommended administration procedure while taking Metformin twice or once daily with meals.

Different diabetic drugs are frequently administered to patients. Additionally, Ozempic and Metformin may be given for combination use in diabetics. 

It’s also vital to keep in mind that taking the two at the same time could have unwanted effects. For example, some people might initially have decreased blood sugar levels. But over time, the body adapts, and the two collaborate harmoniously to provide the best outcomes.

Final Remarks

Diabetes can become a potentially fatal condition if neglected since the body’s inability to create enough insulin can harm the eyes, kidneys, induce strokes, have an adverse effect on the heart, and increase mortality.

The good news is that years of research have improved our knowledge of the illness. By offering practical and efficient treatment options, drugs like Trulicity and Metformin have improved the quality of life for people with type 2 diabetes.

In addition to taking the two medications as prescribed to help you control your blood sugar levels, it’s critical to follow a balanced diet and receive regular exercise.

Furthermore, if you are having difficulty, you should seek the advice of your healthcare provider.

Elevate your diabetes management journey with Better You Rx, where we’re dedicated to your well-being. Our commitment goes beyond prescriptions – we offer tailored solutions that align with your unique needs. When it comes to effective diabetes control, Trulicity and Metformin aren’t just medications; they’re partners in helping you achieve a healthier, happier life.

Experience the difference at Better You Rx, where our expert team provides comprehensive guidance, compassionate care, and personalized solutions that cater to you. Your health is our expertise, and together, we’ll pave the way to a better you. Consult us today to embark on a diabetes management journey that’s truly transformative.

Choose Better You Rx for a holistic approach to diabetes care – it’s not just about prescriptions; it’s about your well-being. Let’s work hand in hand for your healthiest future.

Sign Up For Newsletter

Join 60.000+ Subscribers and get a new discount coupon on every Saturday.


PO Box 29631, Mississauga RPO Central Parkway, ON L5A 4H2

Contact Us


Welcome to Better youRx, where your well-being is our top priority. We are a leading pharmacy, committed to providing you with a wide range of medications, including insulin and diabetes supplies, along with an array of essential healthcare products. Our mission is to empower you on your journey to better health by offering high-quality pharmaceuticals and exceptional customer care.

Our Payment Partners :

Copyright © 2023 BetteryouRX. All Rights Reserved.

Add to cart