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Activelle 1/.5mg

Original price was: $100.00.Current price is: $90.95.

Activelle is a hormone replacement therapy (HRT) medication used to treat various symptoms associated with menopause in women. This medication, which contains a combination of estrogen (estradiol) and progestogen (norethisterone acetate), helps alleviate symptoms such as hot flashes, night sweats, and vaginal dryness. Activelle is also indicated for the prevention of osteoporosis in postmenopausal women at high risk of future fractures.

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Activelle contains two active ingredients: estradiol (an estrogen) and norethisterone acetate (a progestogen). Estradiol is identical to the endogenously produced hormone and helps in replenishing the decrease in estrogen experienced during menopause. Norethisterone acetate is a synthetic form of progesterone, which complements the action of estradiol by providing endometrial protection, thereby reducing the risk of endometrial hyperplasia and cancer.


The balanced combination of these hormones helps in relieving the uncomfortable symptoms of menopause by replacing the estrogen that the ovaries no longer produce. It’s available in the form of tablets, which are usually taken orally.

Additional information


Activelle is taken orally, with or without food, typically once a day, following the same schedule each day to maintain consistent hormone levels in the body. It’s essential to take this medication as prescribed by a physician. The dosage and duration of the treatment are individualized and should be re-evaluated periodically. Women who are postmenopausal and have not undergone a hysterectomy are generally advised to take a combination of HRT to avoid the risk of endometrial cancer associated with estrogen-only therapy.

Side Effects

● Headaches ● Breast tenderness or pain ● Abdominal pain ● Nausea ● Irregular vaginal bleeding or spotting ● Weight changes ● Mood changes


Store Activelle at room temperature, away from excessive heat and moisture. Do not keep it in the bathroom. Ensure it is kept out of reach of children and pets. Medications should not be disposed of via wastewater or household waste. Return any unused medicine to a pharmacy for proper disposal.

Special Precautions

Before starting treatment with Activelle, a thorough personal and family medical history should be taken by a healthcare professional. Regular check-ups, including breast examinations and mammograms, should be carried out per current practice guidelines. Women with a history of breast cancer, blood clots, unexplained vaginal bleeding, liver disease, or those who are pregnant should not use Activelle. Smoking and alcohol may increase the risk of certain side effects, and thus, women are advised to minimize or avoid these while taking Activelle.


If an overdose is suspected, contact a healthcare provider immediately. Overdose of Activelle can lead to severe nausea, vomiting, and vaginal bleeding. Women are advised to follow the prescribed dosage and consult their healthcare provider if they miss a dose instead of doubling up on subsequent doses.


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