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Ketoprofen SR

Original price was: $200.00.Current price is: $189.00.

Ketoprofen SR’s mechanism of action involves inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins play a key role in the inflammation process, pain, and fever generation. By inhibiting COX, ketoprofen SR effectively reduces the levels of prostaglandins, leading to decreased inflammation, pain, and fever.



Ketoprofen SR (Sustained Release) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, and for alleviating menstrual pain. Ketoprofen SR is designed to gradually release the medication in the body, offering longer-lasting pain relief than its immediate-release counterparts. This formulation helps manage symptoms with reduced dosing frequency, improving patient compliance.

Additional information


Ketoprofen SR is indicated for:

● Relief of signs and symptoms of osteoarthritis and rheumatoid arthritis.
● Treatment of mild to moderate pain.
● Management of menstrual pain.

Patients are advised to:

● Take Ketoprofen SR exactly as prescribed by their healthcare provider.
● Avoid cutting, breaking, or chewing the sustained-release tablets to prevent altering the drug release properties.
● Take with food or milk to reduce gastrointestinal side effects.


● Ketoprofen SR should be taken as directed by the healthcare provider, usually once daily due to its sustained-release formulation.
● Swallow the tablets whole with a full glass of water.


● Ketoprofen SR can increase the risk of severe cardiovascular thrombotic events, myocardial infarction, and stroke. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.
● Long-term use may lead to an increased risk of serious gastrointestinal events, including bleeding, ulceration, and perforation of the stomach or intestines.
● Ketoprofen SR should be used with caution in patients with renal or hepatic impairment.

Drug Interactions:

● Concurrent use with other NSAIDs or corticosteroids may increase the risk of gastrointestinal ulcerations or bleeding.
● Anticoagulants or selective serotonin reuptake inhibitors (SSRIs) may have heightened risks of bleeding if used in conjunction with Ketoprofen SR.
● Blood pressure-lowering effects of antihypertensives may be reduced.

Side Effects

● Gastrointestinal discomfort
● Nausea
● Dizziness
● Headache

Serious side effects requiring medical attention include:

● Gastrointestinal bleeding
● Cardiovascular thrombotic events
● Hepatic or renal impairment signs
● Severe skin reactions


● Store in a cool, dry place away from direct sunlight.
● Keep the medication in its original container, tightly closed, and out of reach of children.

Special Precautions

Before starting Ketoprofen SR, patients should inform their healthcare provider if they:

● Have a history of ulcers or gastrointestinal bleeding.
● Suffer from high blood pressure or heart diseases.
● Have kidney or liver problems.
● Are pregnant, planning to become pregnant, or breastfeeding.


An overdose of Ketoprofen SR may lead to symptoms such as nausea, vomiting, stomach pain, drowsiness, and blurred vision. In severe cases, it may cause gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, and coma. Immediate medical attention should be sought in case of overdose suspicion.


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